In Vivo and In Vitro Evaluation of Hair Growth Potential of Cacumen Platycladi, and GC-MS Analysis of the Active Constituents of Volatile Oil

    March 2019 in “ Journal of ethnopharmacology ”
    Yan Zhang, Shanshan Chen, Fan-Zhi Qu … Yuqing Zhao
    Studysummary This study found that Cacumen Platycladi volatile oil promotes dermal papilla cell proliferation and enhances hair growth in mice, outperforming minoxidil and showing no obvious cytotoxic effects.
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    Research cited in this study 21

    1. Mechanism of Action of Herbs and Their Active Constituents Used in Hair Loss Treatment Fitoterapia · 2016
    2. Preventive Effects of Cedrol Against Alopecia in Cyclophosphamide-Treated Mice Environmental Toxicology and Pharmacology · 2016
    3. Hair Growth Promoting Activity of Cedrol Isolated from the Leaves of Platycladus Orientalis Biomedicine & Pharmacotherapy · 2016
    4. Inhibitory Activities of Some Traditional Chinese Herbs Against Testosterone 5α-Reductase and Effects of Cacumen Platycladi on Hair Regrowth in Testosterone-Treated Mice Journal of Ethnopharmacology · 2015
    5. Red Ginseng Extract Promotes Hair Growth in Cultured Human Hair Follicles Journal of Medicinal Food · 2014
    6. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014
    7. Insulin-Like Growth Factor-1: Roles in Androgenetic Alopecia Experimental Dermatology · 2014
    8. Hair Growth-Promoting Activity of Hot Water Extract of Thuja Orientalis BMC Complementary and Alternative Medicine · 2013
    9. Persistent Sexual Side Effects of Finasteride: Could They Be Permanent? The Journal of Sexual Medicine · 2012
    10. Dissecting the Bulge in Hair Regeneration Journal of Clinical Investigation · 2012
    11. Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss The Journal of Sexual Medicine · 2011
    12. The Establishment and Characterization of Immortalized Human Dermal Papilla Cells and Their Hair Growth Promoting Effects Journal of Dermatological Science · 2010
    13. The Cycling Hair Follicle as an Ideal Systems Biology Research Model Experimental Dermatology · 2010
    14. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005
    15. The Extract of Thuja Occidentalis Semen Inhibited 5α-Reductase and Androgenetic Alopecia in B6CBAF1/J Hybrid Mice Journal of dermatological science · 2003
    16. Promoted Growth of Murine Hair Follicles Through Controlled Release of Vascular Endothelial Growth Factor Biomaterials · 2002
    17. Local Injection of Hepatocyte Growth Factor/Scatter Factor Alters Cyclic Growth of Murine Hair Follicles Journal of Investigative Dermatology · 1998
    18. Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells Journal of Investigative Dermatology · 1996
    19. Melanogenesis During the Anagen-Catagen-Telogen Transformation of the Murine Hair Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    20. The Therapeutic Use of Topical Minoxidil Dermatologic Clinics · 1990
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