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    KF19418, A New Compound for Hair Growth Promotion in Vitro and in Vivo Mouse Models

    Akio Shirai, Junichi Ikeda, Sagano Kawashima … Toshikazu Kamiya
    Studysummary This study found that KF19418 stimulated hair follicle growth in vitro and accelerated hair regrowth in a mouse alopecia model, with effects comparable to minoxidil.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 14

    1. Regulation Mechanisms of Hair Growth Current problems in dermatology · 2015
    2. Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1999
    3. Proanthocyanidins from Grape Seeds Promote Proliferation of Mouse Hair Follicle Cells In Vitro and Convert Hair Cycle In Vivo Acta dermato-venereologica · 1998
    4. Hair Follicle Elongation in Organ Culture of Skin from Newborn and Adult Mice Journal of Dermatological Science · 1998
    5. Effect of Minoxidil Sulfate and Pinacidil on Single Potassium Channel Current in Cultured Human Outer Root Sheath Cells and Dermal Papilla Cells Journal of Dermatological Science · 1994
    6. Potassium Channel Conductance as a Control Mechanism in Hair Follicles Journal of Investigative Dermatology · 1993
    7. Organ Culture of Human Hair Follicles in Serum-Free Medium Archives of Dermatological Research · 1993
    8. Potassium Channel Openers Stimulate DNA Synthesis in Mouse Epidermal Keratinocyte and Whole Hair Follicle Cultures Skin Pharmacology and Physiology · 1993
    9. Effects of Cepharanthine and Minoxidil on Proliferation, Differentiation, and Keratinization of Cultured Cells from the Murine Hair Apparatus Archives of Dermatological Research · 1992
    10. Potassium Channel Conductance: A Mechanism Affecting Hair Growth Both In Vitro and In Vivo Journal of Investigative Dermatology · 1992
    11. Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles Journal of Investigative Dermatology · 1990
    12. Minoxidil Stimulates Mouse Vibrissae Follicles in Organ Culture Journal of Investigative Dermatology · 1989
    13. Minoxidil Stimulates Cutaneous Blood Flow in Human Balding Scalps: Pharmacodynamics Measured by Laser Doppler Velocimetry and Photopulse Plethysmography Journal of Investigative Dermatology · 1984
    14. Hypertrichosis Due to Minoxidil British Journal of Dermatology · 1979

    Related research 10

    1. Scalp Threading – New Treatment Option for Androgenetic Alopecia South Florida Journal of Health · 2022
    2. Evaluation of the Effect of Topically Applied Methylsulfonylmethane and Their Combination with Minoxidil Solution for Improvement of Hair Growth in Male Mice Wiadomości lekarskie (Warsaw Poland) · 2022
    3. Androgenetic Alopecia Pattern Hair Regrowth in Patients with Alopecia Areata Treated with Oral JAK Inhibitors Journal of The American Academy of Dermatology · 2020
    4. Hair Loss (Alopecia or Baldness) 2018
    5. Treatments of Hereditary Hair Loss (Alopecia) 2018
    6. Topical Products for Human Hair Regeneration: A Comparative Study on an Animal Model Annals of Dermatology · 2016
    7. Androgenetic Alopecia and Its Remedies: A Review Journal of drug discovery and therapeutics · 2014
    8. Minoxidil to Treat Androgenetic Alopecia in Men and Women: What Is It and How Does It Work? American Journal of Medicine and Medical Sciences · 2014
    9. Therapy Of Androgenetic Alopecia In Women With Minoxidil Solution Gynäkologische Endokrinologie · 2009
    10. KF19418, A New Compound for Hair Growth Promotion in Vitro and in Vivo Mouse Models Journal of Dermatological Science · 2001