Effect of Minoxidil Sulfate and Pinacidil on Single Potassium Channel Current in Cultured Human Outer Root Sheath Cells and Dermal Papilla Cells

    July 1994 in “ Journal of Dermatological Science ”
    Yutaka Nakaya, Hiroyasu Hamaoka, Shoji Kato, Seiji Arase
    Studysummary This study found that minoxidil sulfate and pinacidil did not activate K channel currents in hair follicles, suggesting their effect on hair growth might occur through other mechanisms like increased blood flow.
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    Research cited in this study 7

    1. Potassium Channel Conductance as a Control Mechanism in Hair Follicles Journal of Investigative Dermatology · 1993
    2. Potassium Channel Conductance as a Control Mechanism in Hair Follicles Journal of Investigative Dermatology · 1993
    3. Potassium Channel Conductance: A Mechanism Affecting Hair Growth Both In Vitro and In Vivo Journal of Investigative Dermatology · 1992
    4. Localization of Minoxidil Sulfotransferase in Rat Liver and the Outer Root Sheath of Anagen Pelage and Vibrissa Follicles Journal of Investigative Dermatology · 1991
    5. Immunohistochemical and Autoradiographic Findings Suggest Minoxidil Is Not Localized in Specific Cells of Vibrissa, Pelage, or Scalp Follicles Cell and Tissue Research · 1990
    6. Minoxidil-Induced Hypertrichosis: Treatment with Calcium Thioglycolate Depilatory PubMed · 1977
    7. Minoxidil-Induced Hypertrichosis: Treatment with Calcium Thioglycolate Depilatory Agent Southern Medical Journal · 1977