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research Effect of Minoxidil Sulfate and Pinacidil on Single Potassium Channel Current in Cultured Human Outer Root Sheath Cells and Dermal Papilla Cells

16 citations , July 1994 in “Journal of Dermatological Science”

Minoxidil sulfate and pinacidil may promote hair growth through increased blood flow, not by activating potassium channels.

research Inhibitory Effects of the ATP-Sensitive Potassium Channel Openers Cromakalim, Pinacidil, and Minoxidil on the Carbachol-Response Curve in Porcine Detrusor Muscle

3 citations , March 2012 in “Arab Journal of Urology”

Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.

research Output Displacement Error Evaluation of Multi-Degree-of-Freedom Mechanism Under Arbitrary Load Directions: Proposal of Evaluation Method and Stiffening of 3-Degree-of-Freedom Spatial Parallel Mechanism (Mechanical Dynamics, Measurement, Automatic Control)

January 2005 in “日本機械学會論文集. C編”

Minoxidil sulfate and pinacidil promote hair growth likely by increasing blood flow, not by activating K channels.

research Androgenetic Alopecia

5 citations , May 1994 in “Facial plastic surgery clinics of North America”

Minoxidil was promising for treating male and female pattern baldness in 1994, but more research on genetics and other treatments was needed.

Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells

research Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells

1 citations , August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

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community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)

in Technology 11 upvotes 2 months ago

Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.

community Creatine is the opposite of minoxidil !

in Research/Science 323 upvotes 1 month ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

community P-1075: a BETTER version of Minoxidil

in Research/Science 1 month ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

community Sustaining minoxidil dependent hairs?

in Research/Science 9 upvotes 1 year ago

Minoxidil-dependent hairs fall out if minoxidil is stopped. New treatments like GT20029, FOL055, or TDM105795 might help sustain these hairs.