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    Glossary Pinacidil

    Pinacidil is a potassium channel opener that has been studied for its potential role in promoting hair growth and treating hair loss. It works by enhancing blood flow to hair follicles and may stimulate hair regrowth by prolonging the anagen (growth) phase of the hair cycle. Unlike other hair loss treatments, pinacidil is not a topical minoxidil derivative but shares similar mechanisms in promoting vasodilation and improving follicular health. Its relevance lies in its potential as an alternative or adjunct therapy for conditions like androgenetic alopecia.

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    Research 30 of 47

    1. Effect of minoxidil sulfate and pinacidil on single potassium channel current in cultured human outer root sheath cells and dermal papilla cells Journal of Dermatological Science · 1994 · 16 citations
    2. Inhibitory effects of the ATP-sensitive potassium channel openers cromakalim, pinacidil and minoxidil on the carbachol–response curve in porcine detrusor muscle Arab Journal of Urology · 2012 · 3 citations
    3. Potassium Channel Openers Stimulate DNA Synthesis in Mouse Epidermal Keratinocyte and Whole Hair Follicle Cultures Skin Pharmacology and Physiology · 1993 · 31 citations
    4. Effect of K+ channel openers on K+ channel in cultured human dermal papilla cells. PubMed · 1997 · 20 citations
    5. Enhanced in vitro hair growth at the air-liquid interface: minoxidil preserves the root sheath in cultured whisker follicles In Vitro Cellular & Developmental Biology - Animal · 1993 · 12 citations
    6. ANDROGENETIC ALOPECIA Facial plastic surgery clinics of North America · 1994 · 5 citations
    7. Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome K<sub>ATP</sub>Channel Mutations in Intact Cells 2023 · 1 citations
    8. Ultrastructural Localization and Quantification of Extracellular Calcium Binding Sites in Mouse Vibrissa and Human Scalp Follicles Skin Pharmacology and Physiology · 1993 · 1 citations
    9. Hormonal Control of Cardiac Action Potential Phase 1 Currents in the Brugada Syndrome Revista Argentina de Cardiología · 2014
    10. 任意方向の負荷に対する多自由度機構の出力変位誤差評価 : 評価法の提案と3自由度空間パラレルメカニズムの高剛性化(機械力学,計測,自動制御) 日本機械学會論文集. C編 · 2005
    11. ENHANCED IN VITRO HAIR GROWTH AT THE AIR-LIQUID MINOXIDIL PRESERVES THE ROOT SHEATH IN CULTURED WHISKER FOLLICLES INTERFACE: 1993
    12. The Role of ATP-Sensitive Inward Rectifier Potassium Channels In The Regulation of Reactive Oxygen Species In The Western Honey Bee, APIS Mellifera L. 2022
    13. Drug-Induced Hair Loss and Hair Growth Drug Safety · 1994 · 147 citations
    14. K <sub>ATP</sub> Channels and Cardiovascular Disease Circulation Research · 2013 · 144 citations
    15. Drug Reactions Affecting Hair: Diagnosis Dermatologic Clinics · 2007 · 85 citations
    16. Drug-Induced Hair Disorders Current Drug Safety · 2006 · 40 citations
    17. Comparison of the effects of the K+-channel openers cromakalim and minoxidil sulphate on vascular smooth muscle British Journal of Pharmacology · 1991 · 33 citations
    18. Characterization of minoxidil/hydroxypropyl-β-cyclodextrin inclusion complex in aqueous alginate gel useful for alopecia management: Efficacy evaluation in male rat European Journal of Pharmaceutics and Biopharmaceutics · 2017 · 19 citations
    19. KF19418, a new compound for hair growth promotion in vitro and in vivo mouse models Journal of Dermatological Science · 2001 · 15 citations
    20. Alopecia - the search for novel agents continues Expert Opinion on Therapeutic Patents · 1997 · 11 citations
    21. Male androgenetic alopecia (Part II) The Journal of Men's Health & Gender · 2005 · 9 citations
    22. Chapter 20. Pathogenesis and Treatment of Alopecias Annual Reports in Medicinal Chemistry · 1989 · 8 citations
    23. Induction of Vascular Endothelial Growth Factor Messenger Ribonucleic Acid Expression in Stored Micrografts by Aminoguanidine Dermatologic Surgery · 2005 · 1 citations
    24. Expanding the therapeutic landscape of minoxidil for androgenetic alopecia: topical, oral and sublingual formulations Frontiers in Pharmacology · 2026
    25. Management OF Patients with Polycystic Ovary Syndrom Neliti · 2025
    26. Phytochemicals as emerging therapeutic agents for alopecia treatment Elsevier eBooks · 2020
    27. Menopause - Andropause - Anti-Aging 2008, 11.-13. Dezember 2008, Wien - Abstracts Journal für Kardiologie (Krause & Pachernegg GmbH) · 2008
    28. Drug-induced changes in hair growth Drugs & Therapy Perspectives · 1994
    29. Effect of Allium cepa (red) and Angelica gigas Nakai on Hair-growth Promotion in C57BL/6 Mice JoLS Journal of Life Sciences · 2020
    30. Glibenclamide reverses cromakalim-induced anti-ischemic effect in conscious rabbits Pharmacological Research · 1992 · 1 citations