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    Glossary Pinacidil

    Pinacidil is a potassium channel opener that has been studied for its potential role in promoting hair growth and treating hair loss. It works by enhancing blood flow to hair follicles and may stimulate hair regrowth by prolonging the anagen (growth) phase of the hair cycle. Unlike other hair loss treatments, pinacidil is not a topical minoxidil derivative but shares similar mechanisms in promoting vasodilation and improving follicular health. Its relevance lies in its potential as an alternative or adjunct therapy for conditions like androgenetic alopecia.

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    Research 30 of 51

    1. Effect of minoxidil sulfate and pinacidil on single potassium channel current in cultured human outer root sheath cells and dermal papilla cells Journal of Dermatological Science · 1994 · 16 citations
    2. Inhibitory effects of the ATP-sensitive potassium channel openers cromakalim, pinacidil and minoxidil on the carbachol–response curve in porcine detrusor muscle Arab Journal of Urology · 2012 · 3 citations
    3. Potassium Channel Openers Stimulate DNA Synthesis in Mouse Epidermal Keratinocyte and Whole Hair Follicle Cultures Skin Pharmacology and Physiology · 1993 · 31 citations
    4. Effect of K+ channel openers on K+ channel in cultured human dermal papilla cells. PubMed · 1997 · 20 citations
    5. Enhanced in vitro hair growth at the air-liquid interface: minoxidil preserves the root sheath in cultured whisker follicles In Vitro Cellular & Developmental Biology - Animal · 1993 · 12 citations
    6. ANDROGENETIC ALOPECIA Facial plastic surgery clinics of North America · 1994 · 5 citations
    7. Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome K<sub>ATP</sub>Channel Mutations in Intact Cells 2023 · 1 citations
    8. Ultrastructural Localization and Quantification of Extracellular Calcium Binding Sites in Mouse Vibrissa and Human Scalp Follicles Skin Pharmacology and Physiology · 1993 · 1 citations
    9. Hormonal Control of Cardiac Action Potential Phase 1 Currents in the Brugada Syndrome Revista Argentina de Cardiología · 2014
    10. 任意方向の負荷に対する多自由度機構の出力変位誤差評価 : 評価法の提案と3自由度空間パラレルメカニズムの高剛性化(機械力学,計測,自動制御) 日本機械学會論文集. C編 · 2005
    11. ENHANCED IN VITRO HAIR GROWTH AT THE AIR-LIQUID MINOXIDIL PRESERVES THE ROOT SHEATH IN CULTURED WHISKER FOLLICLES INTERFACE: 1993
    12. The Role of ATP-Sensitive Inward Rectifier Potassium Channels In The Regulation of Reactive Oxygen Species In The Western Honey Bee, APIS Mellifera L. 2022
    13. Novel and Established Potassium Channel Openers Stimulate Hair Growth In Vitro: Implications for their Modes of Action in Hair Follicles Journal of Investigative Dermatology · 2005 · 35 citations
    14. Potassium channel openers: therapeutic potential in cardiology and medicine Expert Opinion on Pharmacotherapy · 2001 · 25 citations
    15. Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process Bioorganic & Medicinal Chemistry · 2011 · 13 citations
    16. Drug-Induced Hair Loss and Hair Growth Drug Safety · 1994 · 147 citations
    17. K <sub>ATP</sub> Channels and Cardiovascular Disease Circulation Research · 2013 · 144 citations
    18. K channel therapeutics at the bedside Journal of Molecular and Cellular Cardiology · 2005 · 119 citations
    19. Drug Reactions Affecting Hair: Diagnosis Dermatologic Clinics · 2007 · 85 citations
    20. Hair growth and rejuvenation: An overview Journal of Dermatological Treatment · 2010 · 81 citations
    21. Small molecules and small molecule drugs in regenerative medicine Drug Discovery Today · 2013 · 51 citations
    22. Drug-Induced Hair Disorders Current Drug Safety · 2006 · 40 citations
    23. Comparison of the effects of the K+-channel openers cromakalim and minoxidil sulphate on vascular smooth muscle British Journal of Pharmacology · 1991 · 33 citations
    24. Limitations of human occipital scalp hair follicle organ culture for studying the effects of minoxidil as a hair growth enhancer Experimental Dermatology · 2004 · 30 citations
    25. Characterization of minoxidil/hydroxypropyl-β-cyclodextrin inclusion complex in aqueous alginate gel useful for alopecia management: Efficacy evaluation in male rat European Journal of Pharmaceutics and Biopharmaceutics · 2017 · 19 citations
    26. KF19418, a new compound for hair growth promotion in vitro and in vivo mouse models Journal of Dermatological Science · 2001 · 15 citations
    27. Alopecia - the search for novel agents continues Expert Opinion on Therapeutic Patents · 1997 · 11 citations
    28. Bisindolylmaleimide Protein-Kinase-C Inhibitors Delay the Decline in DNA Synthesis in Mouse Hair Follicle Organ Cultures Skin Pharmacology and Physiology · 1997 · 11 citations
    29. Male androgenetic alopecia (Part II) The Journal of Men's Health & Gender · 2005 · 9 citations
    30. Chapter 20. Pathogenesis and Treatment of Alopecias Annual Reports in Medicinal Chemistry · 1989 · 8 citations