Novel and Established Potassium Channel Openers Stimulate Hair Growth In Vitro: Implications for Their Modes of Action in Hair Follicles

March 2005 in “ Journal of Investigative Dermatology ”

G C Davies, M. Julie Thornton, Tracey J. Jenner, Yi‐Ju Chen, John Bondo Hansen, Richard D. Carr, Valerie A. Randall

potassium channel openers minoxidil diazoxide K_ATP channels potassium channel inhibitors tolbutamide glibenclamide hair follicle growth Rogaine

Studysummary In this in vitro study, minoxidil, diazoxide, and the novel compound NNC 55-0118 increased hair follicle growth, supporting deer follicles as a viable bioassay for ATP-sensitive potassium channel modulators.

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