25 citations
,
December 2001 in “Expert Opinion on Pharmacotherapy”
Potassiumchannelopeners show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.
6 citations
,
April 2014 in “European journal of medicinal chemistry”
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassiumchannel opener.
Dr. Muñoz's discovery suggests that targeting potassiumchannels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassiumchannelopeners, as well as bioelectric devices and direct growth factor applications.
KX-826 Max combines KX-826, Kopyrrol, and Kopexil as a potential alternative to minoxidil and finasteride for hair loss, but users express skepticism about its effectiveness and high cost. Some users believe traditional treatments like minoxidil, finasteride, and others are more reliable.
Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.
This post and conversation are about the effects of Minoxidil on renal electrolytes transport in the Loop of Henle. The replies show a lack of interest and a brief summary stating that rectal Minoxidil electrolytes are bad.
Topical diazoxide may be a promising hair regrowth treatment, especially for those who don't respond to minoxidil, as it activates potassiumchannels without needing sulfation. It appears safe for topical use, avoiding systemic effects seen in oral use.