Examination of Androgenetic Alopecia with Serum Biomarkers

September 2020 in “ Journal of Cosmetic Dermatology ”

Ali Balik, Zeynep Balık, Akın Aktaş, Salim Neselioglu, Ercan Karabulut, Aysun Bay Karabulut

androgenetic alopecia serum biomarkers insulin-like growth factor-1 vitamin D free oxygen radicals oxidative stress androgens microinflammation fibrosis AGA IGF-1

TLDR Serum biomarkers like insulin-like growth factor-1 and vitamin D may help diagnose androgenetic alopecia.

A study suggests that certain serum biomarkers, such as insulin-like growth factor-1 and vitamin D, could be used as potential diagnostic tools for androgenetic alopecia (AGA), as they were found to be significantly different in individuals with the condition compared to those without. The study found that individuals with AGA have higher levels of free oxygen radicals and oxidative stress, indicating that androgens may cause hair loss by inducing microinflammation and fibrosis. The study emphasizes the need to consider other pathogenic pathways due to the limited success of current treatments. Overall, serum biomarkers may play a role in the development of AGA, and further research is needed to fully understand this connection.

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