TLDR Men with certain types of baldness at age 45 may have a higher risk of colon cancer and colorectal adenoma.
The study conducted from 1992 to 2010 with 32,782 men for cancer analysis and 29,770 men for adenoma analysis found that male pattern baldness at age 45 was associated with an increased risk of colorectal neoplasia. Men with frontal-only baldness and frontal-plus-mild-vertex baldness had a 29% and 31% increased risk of colon cancer, respectively, compared to those with no baldness. Additionally, frontal-only baldness was associated with a significant increased risk of colorectal adenoma. The study suggests a potential link between the insulin pathway and tubular adenomas in this context, rather than excess androgenicity, which is thought to connect baldness with prostate cancer. The authors note limitations such as self-reported baldness and limited racial generalizability, and they call for further research to confirm their findings and explore the underlying mechanisms.
48 citations,
October 2014 in “International Journal of Cardiology” People with alopecia are at higher risk for heart disease and have more heart-related risk factors.
28 citations,
September 2014 in “Journal of Clinical Oncology” Men with baldness at the front and top of their head at age 45 may have a higher risk of aggressive prostate cancer.
37 citations,
April 2013 in “Plastic and Reconstructive Surgery” Genetic and environmental factors, like smoking and exercise, affect male hair loss.
11 citations,
January 2010 in “Springer eBooks” 
26 citations,
June 2000 in “Journal of The American Academy of Dermatology” Men with balding at age 45 had higher IGF-1 and lower IGFBP-3, suggesting these factors might be important in male pattern baldness.
22 citations,
May 2000 in “American Journal of Clinical Dermatology” Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.
9 citations,
March 2018 in “International Journal of Cancer” Men with frontal male pattern baldness may have a higher risk of gastric cancer.
28 citations,
September 2014 in “Journal of Clinical Oncology” Men with baldness at the front and top of their head at age 45 may have a higher risk of aggressive prostate cancer.
20 citations,
August 2016 in “International Journal of Cancer” Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.
57 citations,
November 2017 in “Nature Communications” Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.
3 citations,
December 2014 in “Journal of Clinical Oncology” Men with a certain baldness pattern at age 40-50 may have a higher risk of aggressive prostate cancer.
