Increasing the Percutaneous Absorption and Follicular Penetration of Retinal by Topical Application of Proretinal Nanoparticles

    Benchaphorn Limcharoen, Pattrawadee Toprangkobsin, Wijit Banlunara … Alexa Patzelt
    Studysummary This study observed that proretinal nanoparticles delivered significantly higher concentrations of retinal to the stratum corneum and hair follicles compared to non-particulate forms, potentially improving topical retinoid therapy.
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    Research cited in this study 5

    1. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    2. Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells by Hair Follicles and Their Transport in Mice ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    3. Hair Follicles, Their Disorders, and Their Opportunities Drug Discovery Today: Disease Mechanisms · 2008
    4. Follicular Penetration of Topically Applied Caffeine via a Shampoo Formulation Skin Pharmacology and Physiology · 2007
    5. Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005