Epidemiological Landscape of Androgenetic Alopecia in the US: An All of Us Cross-Sectional Study

    February 2025 in “ PLoS ONE ”
    Aditya K. Gupta, Tong Wang, Vasiliki Economopoulos
    TLDR Androgenetic alopecia starts earlier in males than females, with different treatments, and is linked to income, education, alcohol use, and mental health.
    This cross-sectional study using the All of Us dataset analyzed the prevalence and treatment of androgenetic alopecia (AGA) in 266,612 participants in the US. It found that AGA typically begins earlier in males (20-39 years) than in females (60-69 years), with treatment for males often including finasteride and oral minoxidil, while females are prescribed spironolactone and oral minoxidil, with finasteride used post-menopause. The study noted a significant drop in finasteride prescriptions after reports of Post-Finasteride Syndrome in 2011. AGA incidence was higher among individuals with higher income, education, and alcohol use. In females, AGA was more frequently reported in those with anxiety and depression, suggesting a link between AGA and mental health. The study highlights the influence of social determinants on AGA and suggests that addressing AGA may improve overall health management. Limitations include potential inaccuracies in electronic health record data and the exclusion of over-the-counter treatments like topical minoxidil.
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      Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      in Research  864 upvotes 4 months ago
      The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

      community C’est terrible - at my wits end

      in Female  445 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community It’s over. NOTHING has worked.

      in Chat  95 upvotes 2 years ago
      A user who has been trying various treatments for hair loss for four years, with no success. Suggestions include use of minoxidil, finasteride, RU58841, microneedling, supplements and multivitamins, lifestyle changes, scalp biopsy, and SMP.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Dont fucking wait to start finasteride!

      in Chat  372 upvotes 3 years ago
      User baldwarrior85 regrets not starting finasteride earlier to prevent hair loss. Others share their experiences, with some having side effects and others seeing positive results from the treatment.

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