Tight Junction Barriers in Human Hair Follicles – Role of Claudin-1

    August 2018 in “ Scientific reports ”
    Michaela Zorn‐Kruppa, Sabine Vidal-y-Sy, Pia Houdek … Johanna M. Brandner
    Studysummary This study demonstrated that tight junction barriers exist in human hair follicles but are less tight in hair follicle keratinocytes than in interfollicular keratinocytes, highlighting claudin-1's key role in follicle barrier function and growth.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on nature.com →
    Discuss this study in the Community →

    Research cited in this study 7

    1. Tight Junctions Form a Barrier in Porcine Hair Follicles European journal of cell biology · 2015
    2. A Guide to Studying Human Hair Follicle Cycling In Vivo Journal of Investigative Dermatology · 2015
    3. Expression of the Orphan Protein Plet-1 During Trichilemmal Differentiation of Anagen Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    4. Follicular Targeting: A Promising Tool in Selective Dermatotherapy ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    5. Keratins of the Human Hair Follicle International review of cytology · 2005
    6. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    7. An Efficient Method for Isolation of Hair Papillae and Follicle Epithelium from Human Scalp Specimens British journal of dermatology/British journal of dermatology, Supplement · 1993