Necl2 Regulates Epidermal Adhesion And Wound Repair

    September 2009 in “ Development ”
    Adam Giangreco, Kim B. Jensen, Yoshimi Takai … Fiona M. Watt
    Studysummary This study found that overexpression of the intercellular adhesion protein Necl2 in hair follicle stem cells was associated with reduced cell proliferation and delayed wound healing in both cultured cells and transgenic mice.
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    Research cited in this study 7

    1. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis Cell stem cell · 2009
    2. Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008
    3. Scratching the Surface of Skin Development Nature · 2007
    4. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    5. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    6. Transient Activation of Beta-Catenin Signaling in Adult Mouse Epidermis Induces New Hair Follicles, Continuous Activation Maintains Tumors Development · 2004
    7. Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis Development · 2003