Hair Follicle Targeting With Curcumin Nanocrystals: Influence of Formulation Properties on Penetration Efficacy

October 2020 in “ Journal of Controlled Release ”

Olga Pelikh, Ralph W. Eckert, Shashank Reddy Pinnapireddy, Cornelia M. Keck

curcumin nanocrystals hair follicles gel formulations oleogels hydrogels shear-thinning behavior humectants follicular penetration dermal penetration infundibulum curcumin nanocrystals gels

Studysummary This study found that curcumin nanocrystals efficiently penetrated hair follicles down to the lower infundibulum in an ex-vivo pig ear model, regardless of the gel vehicle used, though passive dermal penetration varied with the vehicle’s skin hydrating properties.

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