Particle Size Effect of Curcumin Nanocrystals on Transdermal and Transfollicular Penetration by Hyaluronic Acid-Dissolving Microneedle Delivery

    February 2022 in “ Pharmaceuticals ”
    Hong Xiang, Sai Xu, Jingyuan Li … Xiao Miao
    Studysummary This study found that smaller curcumin nanocrystals (60 nm) enhanced transdermal and transfollicular penetration more effectively than larger sizes, influenced by particle size.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 7

    1. Influence of Nanocrystal Size on the In Vivo Absorption Kinetics of Caffeine After Topical Application European journal of pharmaceutics and biopharmaceutics · 2021
    2. Hair Follicle Targeting and Dermal Drug Delivery with Curcumin Drug Nanocrystals: Essential Influence of Excipients Nanomaterials · 2020
    3. Microneedles Mediated Bioinspired Lipid Nanocarriers for Targeted Treatment of Alopecia Journal of Controlled Release · 2020
    4. Hair Follicle Targeting With Curcumin Nanocrystals: Influence of Formulation Properties on Penetration Efficacy Journal of Controlled Release · 2020
    5. Polymeric Nanoparticles-Based Topical Delivery Systems for the Treatment of Dermatological Diseases Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2013
    6. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    7. Hair Follicles, Their Disorders, and Their Opportunities Drug Discovery Today: Disease Mechanisms · 2008