Influence of Nanocrystal Size on the In Vivo Absorption Kinetics of Caffeine After Topical Application

    July 2021 in “ European journal of pharmaceutics and biopharmaceutics ”
    P. Breuckmann, Martina C. Meinke, Th. Jaenicke … Alexa Patzelt
    Studysummary This study reported that larger caffeine nanocrystals, at 694 nm, increased caffeine bioavailability via transfollicular penetration compared to smaller nanocrystals, especially in long-term serum concentration measurements.
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