Dermal Nanocrystals from Medium Soluble Actives: Physical Stability and Stability Affecting Parameters

    July 2014 in “ European journal of pharmaceutics and biopharmaceutics ”
    Xuezhen Zhai, Jürgen Lademann, Cornelia M. Keck, Rainer H. Müller
    Studysummary This study established a stable formulation for caffeine nanocrystals in specific solvent mixtures, which could be used to test their potential for enhanced hair follicle targeting and penetration.
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    Research cited in this study 3

    1. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    2. Permeation of Topically Applied Caffeine Through Human Skin – A Comparison of In Vivo and In Vitro Data BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology · 2009
    3. Follicular Transport Route: Research Progress and Future Perspectives European journal of pharmaceutics and biopharmaceutics · 2009