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GlossaryNanocrystals

tiny particles a few nanometers in size with unique properties

Nanocrystals are tiny particles that are only a few nanometers in size, often composed of a single crystal structure. They exhibit unique physical and chemical properties due to their small size and high surface area, making them useful in various applications such as drug delivery, electronics, and cosmetics. For instance, in hair care, nanocrystals can enhance the delivery and effectiveness of active ingredients in treatments for conditions like alopecia.

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research Nanocrystals of Medium Soluble Actives: Novel Concept for Improved Dermal Delivery and Production Strategy

61 citations , May 2014 in “International journal of pharmaceutics”

Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.

research Hair Follicle Targeting With Curcumin Nanocrystals: Influence of Formulation Properties on Penetration Efficacy

60 citations , October 2020 in “Journal of Controlled Release”

Curcumin nanocrystals in simple gels effectively penetrate hair follicles, but humectants can reduce this efficacy.

research Hair Follicle Targeting and Dermal Drug Delivery with Curcumin Drug Nanocrystals: Essential Influence of Excipients

32 citations , November 2020 in “Nanomaterials”

Excipients greatly affect how well curcumin nanocrystals penetrate the skin and target hair follicles.

research Influence of Nanocrystal Size on the In Vivo Absorption Kinetics of Caffeine After Topical Application

10 citations , July 2021 in “European journal of pharmaceutics and biopharmaceutics”

Nanoparticles sized between 470 and 750 nm are best for delivering substances like caffeine into hair follicles for absorption.

research Particle Size Effect of Curcumin Nanocrystals on Transdermal and Transfollicular Penetration by Hyaluronic Acid-Dissolving Microneedle Delivery

10 citations , February 2022 in “Pharmaceuticals”

Smaller curcumin nanocrystals penetrate skin and hair follicles better than larger ones.

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