10 citations
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February 2022 in “Pharmaceuticals” This study found that smaller curcumin nanocrystals (60 nm) enhanced transdermal and transfollicular penetration more effectively than larger sizes, influenced by particle size.
12 citations
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February 2022 in “Acta Biomaterialia” In this study, researchers found that dissolving microneedles made with hyaluronic acid enhanced the effectiveness of minoxidil in reducing hair loss and promoting hair growth in alopecia-affected mice more effectively than topical minoxidil alone, while using only 10% of the drug amount.
October 2023 in “Applied materials today” In this study, researchers developed a novel TA-encapsulated microneedle applicator that successfully promoted hair growth and reduced inflammation in a C3H/HeJ mouse model of alopecia areata, potentially offering an improved alternative to existing treatments.
13 citations
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November 2022 in “Biomaterials Science” This study demonstrated that a device combining hyaluronic acid-based dissolving microneedles and lipid polymer hybrid nanoparticles effectively delivered miR-218 to promote hair growth in a shaved mouse model, outperforming topical smear treatment without safety concerns.
3 citations
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January 2025 in “International Journal of Biological Macromolecules” This study found that a microneedle patch containing tofacitinib-loaded nanoparticles significantly increased hair follicle numbers and promoted hair regeneration with less drug compared to daily topical tofacitinib, suggesting it may be an effective strategy for alopecia treatment by reducing dosing frequency and enhancing drug delivery.