Microneedle Mediated Transdermal Delivery of Beta-Sitosterol Loaded Nanostructured Lipid Nanoparticles for Androgenic Alopecia

    September 2022 in “ Drug Delivery ”
    Kousalya Prabahar, Ubaidulla Udhumansha, Nehal M. Elsherbiny, Mona Qushawy
    Studysummary This study found that a transdermal drug delivery system using nanostructured lipid carriers and polymeric microneedles for β-sitosterol significantly enhanced hair growth in testosterone-induced alopecia rats, suggesting potential for treating androgenic alopecia.
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    Research cited in this study 11

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    2. A Systematic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia Natural Products and Bioprospecting · 2020
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    5. Identification of a New Plant Extract for Androgenic Alopecia Treatment Using a Non-Radioactive Human Hair Dermal Papilla Cell-Based Assay BMC Complementary and Alternative Medicine · 2015
    6. Follicular Delivery of Spironolactone via Nanostructured Lipid Carriers for Management of Alopecia International Journal of Nanomedicine · 2014
    7. Effect of Adiantum Capillus-Veneris Linn on an Animal Model of Testosterone-Induced Hair Loss PubMed · 2014
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    10. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-Alpha-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002
    11. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-Alpha-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002