December 2022 in “Revista Medicina Cutánea Ibero-Latino-Americana” This review summarizes current knowledge on the role of the JAK/STAT signaling pathway in alopecia areata and suggests moderate efficacy of systemic inhibitors, with low adverse events but high recurrence rates.
1 citations
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March 2013 in “Revista de Investigaciones Veterinarias del Perú” This study found that a single application of 0.1% aqueous benzalkonium chloride solution effectively treated dermatomycosis caused by Trichophyton species in guinea pigs.
In this study, low-dose oral minoxidil was found to have a favorable safety profile for treating alopecia, with mostly mild side effects, in both general and hypertensive populations.
18 citations
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September 2021 in “Colloids and surfaces. B, Biointerfaces” This study explored the development of polymeric nanoparticles for topical spironolactone delivery, finding that larger nanoparticles (180 nm) enhanced drug targeting to hair follicles significantly more than smaller ones or non-nanoparticle formulations, offering promise for safer acne and alopecia treatments.
47 citations
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September 2013 in “Aaps Pharmscitech” This study found that liquid crystalline nanoparticles formulated with Cremophor surfactants significantly enhanced skin permeation of finasteride compared to lower surfactant concentrations.