Using Bioprinting and Spheroid Culture to Create a Skin Model with Sweat Glands and Hair Follicles

    January 2021 in “ Burns & Trauma ”
    Yijie Zhang, Enhejirigala, Bin Yao … Xiaobing Fu
    Studysummary This study developed an in vitro model revealing that hair follicle spheroids enhanced both sweat gland and hair follicle differentiation within bioprinted scaffolds, while microenvironmental cues supported persistent regeneration.
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    Research cited in this study 8

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    2. Self-Organization Process in Newborn Skin Organoid Formation Inspires Strategy to Restore Hair Regeneration of Adult Cells Proceedings of the National Academy of Sciences of the United States of America · 2017
    3. Macrophages Induce AKT/β-Catenin-Dependent Lgr5+ Stem Cell Activation and Hair Follicle Regeneration Through TNF Nature Communications · 2017
    4. Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair Cell · 2012
    5. Dynamic Signals for Hair Follicle Development and Regeneration Stem Cells and Development · 2011
    6. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    7. Scratching the Surface of Skin Development Nature · 2007
    8. Keratin 17 Modulates Hair Follicle Cycling in a TNFα-Dependent Fashion Genes & Development · 2006