Promises and Pitfalls of Regenerative Therapies for Androgenetic Alopecia: Platelet-Rich Plasma, Photobiomodulation, Stem Cells, and Exosomes

    December 2025 in “ Medical Sciences
    Aditya K. Gupta, Tong Wang, Ryan J. Welter, Robin Unger, Ricardo Mejía
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    TLDR Regenerative therapies show promise for hair regrowth, but more research and standardization are needed.
    The review examines regenerative therapies for androgenetic alopecia, focusing on platelet-rich plasma (PRP), photobiomodulation (PBM), stem cells, and exosomes. PRP is the most studied, showing promise in improving hair density, but its efficacy is limited by inconsistent protocols and a lack of large, high-quality studies. PBM is safe and can stimulate hair regrowth, but its effectiveness as a standalone treatment is inconclusive due to varied study results. Stem cells and exosomes show potential for hair regrowth, but clinical evidence is limited. The review emphasizes the need for standardization, transparency, and safety in these therapies, as their clinical application has outpaced the accumulation of high-quality evidence.
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