Effectiveness of Autologous Platelet-Rich Plasma for Androgenetic Alopecia: A Double-Center, Non-Controlled, Randomized Clinical Study in Vietnam

July 2025 in “ Clinical Cosmetic and Investigational Dermatology ”

Lam Van Nguyen, T. B. T. Nguyen

autologous platelet-rich plasma androgenetic alopecia hair density hair pull test platelet concentrations scalp discomfort PRP AGA

Studysummary This study found that platelet-rich plasma therapy significantly improved hair density and reduced hair shedding in Vietnamese patients with androgenetic alopecia, with high patient satisfaction and minimal side effects.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This study evaluated the effectiveness of autologous platelet-rich plasma (PRP) therapy for androgenetic alopecia (AGA) in 41 Vietnamese patients over three months. It found significant improvements in hair density, increasing from 40.76 ± 14.26 hairs/cm² at baseline to 66.00 ± 18.00 hairs/cm² at week 12, and a reduction in hair loss, with positive hair pull tests decreasing from 75.6% to 12.2%. Higher platelet concentrations correlated with greater hair density improvements. Patient satisfaction was high at 97.6%, with minor adverse effects like itching and scalp discomfort. The study supports PRP as an effective treatment for AGA, despite limitations such as a small sample size, lack of a control group, and short follow-up duration.

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