Effectiveness of Autologous Platelet-Rich Plasma for Androgenetic Alopecia: A Double-Center, Non-Controlled, Randomized Clinical Study in Vietnam

July 2025 in “ Clinical Cosmetic and Investigational Dermatology ”

Lam Van Nguyen, T. B. T. Nguyen

autologous platelet-rich plasma androgenetic alopecia hair density hair pull test platelet concentrations scalp discomfort PRP AGA

TLDR PRP therapy effectively improves hair density and reduces hair loss in androgenetic alopecia.

This study evaluated the effectiveness of autologous platelet-rich plasma (PRP) therapy for androgenetic alopecia (AGA) in 41 Vietnamese patients over three months. It found significant improvements in hair density, increasing from 40.76 ± 14.26 hairs/cm² at baseline to 66.00 ± 18.00 hairs/cm² at week 12, and a reduction in hair loss, with positive hair pull tests decreasing from 75.6% to 12.2%. Higher platelet concentrations correlated with greater hair density improvements. Patient satisfaction was high at 97.6%, with minor adverse effects like itching and scalp discomfort. The study supports PRP as an effective treatment for AGA, despite limitations such as a small sample size, lack of a control group, and short follow-up duration.

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