Platelet-Rich Plasma for Androgenetic Alopecia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

August 2023 in “ Journal of Cutaneous Medicine and Surgery ”

X. Zhang, Yuxiu Ji, MingChun Zhou, Xin Zhou, Yun Xie, Xiaofeng Zeng, Yun Xie, Feng Shao, Chi Zhang

platelet-rich plasma androgenetic alopecia hair density hair count hair diameter placebo adverse reactions PRP AGA

TLDR PRP is effective and safe for increasing hair density in people with hair loss.

A systematic review and meta-analysis of nine randomized controlled trials involving 238 patients was conducted to evaluate the efficacy and safety of Platelet-Rich Plasma (PRP) for Androgenetic Alopecia (AGA). The study found that PRP treatment significantly increased hair density at 3 and 6 months compared to the placebo. However, while PRP also increased hair count and hair diameter compared to the baseline, these increases were not significantly different from the placebo. Only two of the seven studies reported adverse reactions, none of which were serious. Therefore, the study concluded that PRP is an effective and safe treatment for increasing hair density in AGA.

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