A Clinical Trial of Treating Androgenic Alopecia with Mesenchymal Stem Cell Suspension Derived from Autologous Hair Follicle

    June 2023 in “ Plastic and Reconstructive Surgery ”
    Yuyang Gan, Lijuan Du, Hailin Wang, Kaitao Li, Zhexiang Fan, Pingping Sun, Jiaxian Zhang, Zhiqi Hu, Yong Miao
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    TLDR Stem cell therapy from hair follicles effectively treats advanced hair loss with minimal side effects.
    This clinical trial evaluated the efficacy and safety of autologous hair follicle mesenchymal stem cell therapy for treating advanced androgenic alopecia (AGA) in 50 Chinese patients aged 25-45. Healthy hair follicles were extracted and treated to obtain stem cell suspensions, which were injected into the scalp. Results showed an increase in terminal hair and hair shaft diameter in the experimental group, with effects lasting up to 3 months. The treatment was particularly effective for hair follicles with a shaft diameter less than 60 µm, and no significant side effects were reported. The study concluded that this stem cell therapy is effective for treating advanced AGA, with hair shaft diameter serving as a key predictor of treatment success.
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