Platelet-Rich Plasma: Advances and Controversies in Hair Restoration and Skin Rejuvenation

    February 2024 in “ Dermatologic Surgery
    Arianne Shadi Kourosh, Kathyana P. Santiago Mangual, Ronda S. Farah, Medha Rao, Maria Hordinsky, Suleima Arruda, Neil S. Sadick
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    TLDR PRP shows promise for hair and skin treatment, but more research is needed for standard practices.
    The review article "Platelet-Rich Plasma: Advances and Controversies in Hair Restoration and Skin Rejuvenation" provides an update and analysis of the evidence for the use of Platelet-rich plasma (PRP) in hair restoration and skin rejuvenation. The authors conducted a structured review and expert analysis of PubMed publications before October 2023, focusing on recent literature from January 2020 through October 2023. The growing literature supports the utility and benefits of PRP and related autologous products for skin and hair applications, with the strongest evidence for androgenetic alopecia and skin rejuvenation. However, there is a lack of consensus regarding best practices and protocols. The authors call for randomized, controlled trials with uniform metrics comparing outcomes of various compositions of autologous blood products, preparation methods, dosimetry, and frequency of treatments to move beyond expert opinion into consensus, standardization, and more widespread adoption of best practices.
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