Evaluation of Efficacy of Follicular Unit Extraction Versus Follicular Unit Extraction With Platelet Rich Plasma in Treatment of Cicatricial Alopecia

July 2022 in “ Journal of Cosmetic Dermatology ”

Ali Fouad Elariny, Nasser Ghozlan, Sherif Wasief, Aya Elsayed Moussa, Marwa Eldeeb

follicular unit extraction platelet rich plasma cicatricial alopecia hair grafts hair transplantation FUE PRP CA

Studysummary This study found that follicular unit extraction, with or without platelet rich plasma, is effective for hair restoration in cicatricial alopecia, though PRP does not significantly impact graft survival rates. Our plain-language summary of this paper — not a Tressless recommendation.

The study "Evaluation of efficacy of follicular unit extraction versus follicular unit extraction with platelet rich plasma in treatment of cicatricial alopecia" involved 20 patients with cicatricial alopecia (CA) who were divided into two groups. Group A (10 patients) underwent follicular unit extraction (FUE), while Group B (10 patients) underwent FUE with platelet rich plasma (PRP). PRP was injected 1 week before surgery, then monthly after surgery for 3 months. The study found that in Group A, the mean survival rate of hair grafts increased significantly to 78.15% at 12 months. In Group B, the mean survival rate was 69.74% at 12 months. However, there was no significant difference between both groups at any time during the follow-up period. The study concluded that FUE is a preferred procedure for hair restoration in CA with few side effects, and the role of PRP in hair transplantation is controversial as it does not significantly affect the survival rate of hair grafts.

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Research cited in this study

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research Outcome of Follicular Unit Extraction in Cicatricial Alopecia

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Outcome of Intra-Operative Injected Platelet-Rich Plasma Therapy During Follicular Unit Extraction Hair Transplant: A Prospective Randomized Study in Forty Patients

research Outcome of Intra-Operative Injected Platelet-Rich Plasma Therapy During Follicular Unit Extraction Hair Transplant: A Prospective Randomized Study in Forty Patients

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This study found that intra-operative platelet-rich plasma therapy may enhance hair regrowth, increase graft density, and activate dormant follicles more effectively than normal saline in follicular unit extraction hair transplant patients.

research The Role of Hair Restoration Surgery in Primary Cicatricial Alopecia

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research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

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