Evaluation of Efficacy of Follicular Unit Extraction Versus Follicular Unit Extraction With Platelet Rich Plasma in Treatment of Cicatricial Alopecia

    Ali Fouad Elariny, Nasser Ghozlan, Sherif Wasief, Aya Elsayed Moussa, Marwa Eldeeb
    Image of study
    TLDR Adding platelet rich plasma to follicular unit extraction doesn't significantly improve hair graft survival in cicatricial alopecia treatment.
    The study "Evaluation of efficacy of follicular unit extraction versus follicular unit extraction with platelet rich plasma in treatment of cicatricial alopecia" involved 20 patients with cicatricial alopecia (CA) who were divided into two groups. Group A (10 patients) underwent follicular unit extraction (FUE), while Group B (10 patients) underwent FUE with platelet rich plasma (PRP). PRP was injected 1 week before surgery, then monthly after surgery for 3 months. The study found that in Group A, the mean survival rate of hair grafts increased significantly to 78.15% at 12 months. In Group B, the mean survival rate was 69.74% at 12 months. However, there was no significant difference between both groups at any time during the follow-up period. The study concluded that FUE is a preferred procedure for hair restoration in CA with few side effects, and the role of PRP in hair transplantation is controversial as it does not significantly affect the survival rate of hair grafts.
    Discuss this study in the Community →

    Research cited in this study

    17 / 17 results

    Related Community Posts Join

    6 / 171 results

      community How is verteporfin doing in trials?

      in Chat  9 upvotes 1 year ago
      The conversation is about the progress of verteporfin in hair loss trials, with users expressing curiosity about its effectiveness and updates. Specific treatments mentioned include FUE (Follicular Unit Extraction) combined with verteporfin, with one reported case of donor area regrowth after a year, and three patients being monitored post-treatment by Dr. Bloxham with monthly updates on YouTube.

      community Verteporfin and Microneedling

      in Treatments 6 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

    Related Research

    6 / 6 results