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Research

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Reduced Cardiotoxicity and Comparable Efficacy in a Phase III Trial of Pegylated Liposomal Doxorubicin HCl (CAELYX/Doxil) Versus Conventional Doxorubicin for First-Line Treatment of Metastatic Breast Cancer

research Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer

1461 citations , March 2004 in “Annals of oncology”

This study found that in first-line treatment of metastatic breast cancer, pegylated liposomal doxorubicin (PLD) provided similar progression-free survival to doxorubicin with significantly less cardiotoxicity.

Assessment of Cardiovascular Risk and Prevention of Cardiovascular Disease in Women with Polycystic Ovary Syndrome: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome Society

research Assessment of Cardiovascular Risk and Prevention of Cardiovascular Disease in Women with the Polycystic Ovary Syndrome: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society

815 citations , April 2010 in “The Journal of Clinical Endocrinology & Metabolism”

This review examines the relationship between polycystic ovary syndrome and cardiovascular disease risk, but reports no new clinical findings; the panel calls for guidelines to prevent CVD in this population.

research Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation

694 citations , April 2000 in “Nature genetics”

This study found that Msx2-deficient mice exhibit skull and bone formation defects similar to those seen in human MSX2-related conditions, highlighting the gene's importance in skeletal and organ development.

research Selenium for preventing cancer

618 citations , January 2018 in “Cochrane Database of Systematic Reviews”

This study reported that selenium supplements do not reduce cancer risk and may increase the risk of type 2 diabetes and high-grade prostate cancer, while observational studies suggest mixed associations between selenium exposure and cancer incidence.

Deciphering the Function of Canonical Wnt Signals in Development and Disease: Conditional Loss- and Gain-of-Function Mutations of β-Catenin in Mice

research Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of β-catenin in mice

556 citations , September 2008 in “Genes & Development”

This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.

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Community Join

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community Came back from the dead - One year result

477 upvotes 3 months ago

The user experienced significant hair regrowth using finasteride, minoxidil, Nizoral, dermapen, and PRP sessions. They also made lifestyle changes like quitting smoking and alcohol, resulting in thicker and denser hair.

community Can I alternate oral and topical minoxidil?

2 upvotes 1 week ago

Alternating between oral and topical minoxidil is considered, with concerns about staining bed sheets. Oral minoxidil may cause more body hair but is less messy than topical.

community Can plaques and build up on the scalp potentially stop new hairs from growing there?

4 upvotes 2 weeks ago

Scalp build-up may affect hair growth, but experiences vary. Treatments mentioned include ketoconazole, clobetasol, and Head & Shoulders shampoo.

community Can a transplant fill my head?

6 upvotes 3 weeks ago

A 22-year-old is considering a hair transplant to address diffuse thinning and is currently using oral finasteride and minoxidil, with plans to switch to oral dutasteride. They are debating between one or two procedures and are seeking advice on graft numbers and additional treatments like oils and micro-needling.

community Can I start Topical Finasteride and Minoxidil without Doctor's prescription

in Finasteride/Dutasteride 4 upvotes 4 weeks ago

The conversation is about starting topical finasteride and minoxidil for hair loss without a doctor's prescription. The user discusses genetic predisposition to hair loss and mentions lifestyle impacts.

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Learn

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learn Castor oil

a traditional, natural remedy touted for promoting scalp health and hair growth

Does castor oil make hair grow or is it just a myth? There is no published human trial showing castor oil grows hair. It can make hair look and feel better by reducing breakage and adding shine, which is easily mistaken for growth, and it is not approved anywhere as a hair loss treatment.
Castor oil: How do you use it without ending up with greasy hair for days? Use a pea-sized amount of warmed castor oil to avoid greasy hair.

learn Caffeine

the stimulant you know and love can be used topically to stimulate hair

learn Capixyl

learn calcium ascorbate

learn capsicum

learn Dutasteride

Can I use dutasteride without a prescription? All about its sale and regulations. Dutasteride requires a prescription and cannot be used without medical supervision.

learn Ketoconazole

Can I use ketoconazole shampoo if I am pregnant or breastfeeding? Consult your doctor before using ketoconazole shampoo while pregnant or breastfeeding.
Can ketoconazole make hair loss worse before it makes it better? Ketoconazole may cause temporary hair shedding before potential improvement in hair growth.

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Clinics

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All 500 clinic results →

Experts