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Research

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research Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer

1461 citations , March 2004 in “Annals of oncology”

This study found that in first-line treatment of metastatic breast cancer, pegylated liposomal doxorubicin (PLD) provided similar progression-free survival to doxorubicin with significantly less cardiotoxicity.

research Assessment of Cardiovascular Risk and Prevention of Cardiovascular Disease in Women with the Polycystic Ovary Syndrome: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society

815 citations , April 2010 in “The Journal of Clinical Endocrinology & Metabolism”

This review examines the relationship between polycystic ovary syndrome and cardiovascular disease risk, but reports no new clinical findings; the panel calls for guidelines to prevent CVD in this population.

research Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation

694 citations , April 2000 in “Nature genetics”

This study found that Msx2-deficient mice exhibit skull and bone formation defects similar to those seen in human MSX2-related conditions, highlighting the gene's importance in skeletal and organ development.

research Selenium for preventing cancer

618 citations , January 2018 in “Cochrane Database of Systematic Reviews”

This study reported that selenium supplements do not reduce cancer risk and may increase the risk of type 2 diabetes and high-grade prostate cancer, while observational studies suggest mixed associations between selenium exposure and cancer incidence.

research Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of β-catenin in mice

556 citations , September 2008 in “Genes & Development”

This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.

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Community Join

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community Came back from the dead - One year result

477 upvotes 4 months ago

The user experienced significant hair regrowth using finasteride, minoxidil, Nizoral, dermapen, and PRP sessions. They also made lifestyle changes like quitting smoking and alcohol, resulting in thicker and denser hair.

community Can't get dutasteride from dermatologist office

5 upvotes 1 week ago

The user has been using oral minoxidil and finasteride for hair loss with no side effects and wants to try dutasteride but was denied by a dermatologist's office. They suspect the office was promoting Rogaine instead, which is more expensive than their current treatment.

community Can I put these on my scalp???

536 upvotes 1 week ago

Oral minoxidil caused unexpected hair growth on toes and fingers but not on the scalp. Users humorously discussed unconventional hair transplant ideas and noted good circulation as a positive sign.

community Can i apply minoxidil to other areas of my body to work on my scalp (ie does it go systemic enough?)

10 upvotes 2 weeks ago

Minoxidil should be applied directly to the scalp for effectiveness, as applying it elsewhere may not work and could cause systemic effects. Alternatives like oral minoxidil are not suitable for everyone due to potential side effects like severe water retention.

community Can anyone who’s Indian tell me, if this lonitab 2.5mg minoxidil by intas is real?

6 upvotes 2 weeks ago

The conversation confirms that Lonitab 2.5mg minoxidil by Intas is real and effective, with users reporting positive results. Some users suggest splitting the dose to avoid side effects, and others recommend considering reputable brands like Sun Pharmaceutical or Cipla.

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Learn

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learn Castor oil

Thick plant oil used in hair care

Does castor oil make hair grow or is it just a myth? There is no published human trial showing castor oil grows hair. It can make hair look and feel better by reducing breakage and adding shine, which is easily mistaken for growth, and it is not approved anywhere as a hair loss treatment.
Castor oil: Does it help restore lost hair or just strengthen existing hair? No controlled human trial shows that castor oil restores lost hair. It is a cosmetic oil that can make existing hair feel softer, and claims that it strengthens hair are untested.

learn Caffeine

Stimulant used in hair shampoos and lotions

learn Capixyl

learn calcium ascorbate

learn capsicum

learn Dutasteride

Can I use dutasteride without a prescription? All about its sale and regulations. Dutasteride requires a prescription and cannot be used without medical supervision.

learn Ketoconazole

Can I use ketoconazole shampoo if I am pregnant or breastfeeding? Consult your doctor before using ketoconazole shampoo while pregnant or breastfeeding.
Can ketoconazole make hair loss worse before it makes it better? No study shows a minoxidil-style "shed" with ketoconazole shampoo. The label does list increased hair loss (under 1% in trials) and alopecia among reported side effects, so new or increased shedding is worth raising with a doctor or pharmacist.

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