A Response to 'Inconsistent Platelet-Rich Plasma Product from the Food and Drug Administration Cleared Devices: A Retrospective Review of Clinic Data'

    April 2021 in “ Journal of the American Academy of Dermatology ”
    Shilpi Khetarpal
    TLDR Inconsistent platelet counts in PRP are due to varying blood volumes, preparation methods, and analyzer types.
    The response highlighted several unaddressed factors that could account for inconsistent platelet counts in platelet-rich plasma (PRP) products, such as the volume of whole blood used and the specific preparation and analysis methods. The author noted that different systems and devices, including single-spin and gel-separator systems, affect platelet collection and concentration, and emphasized the importance of using validated hematology analyzers for accurate platelet counts. The response also mentioned that PRP preparation systems should consider minimizing inflammatory cells to reduce inflammation and pain during dermatologic applications, particularly for hair loss treatments. The author disclosed a conflict of interest as a consultant for Eclipse Aesthetics.
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