Effect of Platelet-Rich Plasma Versus Saline Solution as a Preservation Solution for Hair Transplantation

June 2020 in “ Plastic and reconstructive surgery. Global open ”

Rasha Abdelkader, Sahar Ahmed Abdalbary, Ibrahim A. Naguib, Kyrillos Makarem

platelet-rich plasma PRP saline solution hair transplantation hair grafts hair regrowth hair density skin recovery graft uptake hair thickness

Studysummary This study found that preserving hair grafts in platelet-rich plasma before implantation significantly improved hair density, graft uptake, and hair thickness compared to saline preservation in hair transplantation patients. Our plain-language summary of this paper — not a Tressless recommendation.

The study compared the effectiveness of Platelet Rich Plasma (PRP) versus saline solution as preservation solutions for hair transplantation in 50 participants. Results indicated that PRP-preserved hair grafts had significantly higher survival rates, better hair density, and improved hair thickness compared to saline-preserved grafts. PRP-preserved grafts showed a graft uptake of 93.3% versus 76.6% in the saline group, with hair density peaking at 203.7 ± 39.9 after 1 year. Participants in the PRP group experienced over 75% hair regrowth after 6 months and reported a mean satisfaction rate of 7.1 out of 10. The study concluded that PRP is a superior preservation solution for hair grafts, enhancing the success of hair transplantation surgeries, though further research with larger sample sizes and longer follow-up is recommended.

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research Platelet-Rich Plasma for Treating Androgenic Alopecia: A Systematic Review

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This study's meta-analysis reported that PRP injections significantly increased hair density compared to baseline and placebo in androgenetic alopecia patients, supporting its use as a beneficial treatment.

research Platelet-Rich Plasma for Androgenetic Alopecia: Does It Work? Evidence from Meta-Analysis

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research Study on the Efficacy of Platelet-Rich Fibrin Matrix in Hair Follicular Unit Transplantation in Androgenetic Alopecia Patients

4 citations , September 2016 in “PubMed”

In this study, platelet-rich fibrin matrix combined with follicular unit transplantation increased hair follicle numbers in men with androgenetic alopecia on the treated side of the scalp after six months.

Outcome of Intra-Operative Injected Platelet-Rich Plasma Therapy During Follicular Unit Extraction Hair Transplant: A Prospective Randomized Study in Forty Patients

research Outcome of Intra-Operative Injected Platelet-Rich Plasma Therapy During Follicular Unit Extraction Hair Transplant: A Prospective Randomized Study in Forty Patients

39 citations , January 2016 in “Journal of Cutaneous and Aesthetic Surgery”

This study found that intra-operative platelet-rich plasma therapy may enhance hair regrowth, increase graft density, and activate dormant follicles more effectively than normal saline in follicular unit extraction hair transplant patients.

research Plasma Rich in Growth Factors for the Treatment of Androgenetic Alopecia

7 citations , June 2015 in “European Journal of Plastic Surgery”

This retrospective study found that treatment with autologous plasma rich in growth factors increased hair density and improved hair follicle health in patients with androgenetic alopecia, with no reported adverse effects.

research Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

164 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

This study found that PRP injections may improve hair density and reduce hair loss in patients with androgenetic alopecia without significant side effects, but further research is needed to confirm efficacy.

research Follicular Unit Extraction Hair Transplant

29 citations , January 2010 in “PubMed”

This review discusses the methodology, limitations, and advantages of Follicular Unit Extraction in hair transplantation without providing new clinical results.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , October 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

In this study, platelet plasma growth factors from patients' autologous plasma improved follicular unit yield in baldness surgery by 15.1% compared to control areas.