TLDR Exosomes show promise for skin and hair rejuvenation, but more research and regulation are needed before they can be widely used.
The document "Exosomes: the latest in regenerative aesthetics" discusses the emerging role of exosomes, or extracellular vesicles, in regenerative aesthetic medicine. These nano-sized vesicles, which play crucial roles in intercellular communication, are being used to target the root causes of skin aging and improve tissue homeostasis. However, there are considerations for their use, including variation in exosome purification, isolation, storage, scalability, and reproducibility. The current research literature does not provide a clear consensus on long-term use for skin rejuvenation or hair restoration, nor does it specify which patients would benefit most from this technology. The document concludes that more clinical studies with proper regulatory oversight are needed, and notes that there are currently no US FDA-approved exosome products on the market for medical indications.
8 citations,
June 2022 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.
5 citations,
March 2022 in “Frontiers in Cell and Developmental Biology” Colostrum-derived exosomes can promote hair growth and may be a promising treatment for hair loss.
38 citations,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
58 citations,
March 2019 in “Experimental Dermatology” Exosomes from human skin cells can stimulate hair growth and could potentially be used for treating hair loss.
71 citations,
January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
87 citations,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
113 citations,
November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
April 2024 in “Biomolecules” Exosomal miRNAs from stem cells can help improve skin health and delay aging.
12 citations,
October 2021 in “Cells” Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.
8 citations,
January 2022 in “Burns and trauma” Skin cell-derived vesicles can help heal skin injuries effectively.
February 2024 in “Journal of Education, Health and Sport” Exosomes can help repair and heal tissues, improving health and vitality.
3 citations,
February 2023 in “International Journal of Molecular Sciences” Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.