Modulation of the Differentiated Phenotype of Keratinocytes of the Hair Follicle and Epidermis

    Norbert E. Fusenig, Alain Limat, H.-J. Stakr, Dirk Breitkreutz
    Studysummary This review examines the differentiation potential of epithelial cells from various sources in hair follicle formation, concluding that complex interactions are required for hair-specific characteristics, which were achieved in vivo but not in vitro.
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    Research cited in this study 19

    1. Outer Root Sheath Cells Organize Into Epidermoid Cyst-Like Spheroids When Cultured Inside Matrigel: A Light-Microscopic and Immunohistological Comparison Between Human ORS Cells and Interfollicular Keratinocytes Cell and Tissue Research · 1994
    2. Organotypic Cocultures as Models to Study Cell-Cell and Cell-Matrix Interactions of Human Hair Follicle Cells Skin Pharmacology and Physiology · 1994
    3. Phenotypic Modulation of Human Hair Matrix Cells by Environmental Influence In Vitro and In Vivo PubMed · 1993
    4. Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells Annals of the New York Academy of Sciences · 1991
    5. Inductive Properties of Hair Follicle Cells Annals of the New York Academy of Sciences · 1991
    6. Keratins 1 and 10 as Regular Constituents of Inner Root Sheath and Cuticle Cells in the Human Hair Follicle PubMed · 1990
    7. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989
    8. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues II: Concomitant and Mutually Exclusive Synthesis of Trichocytic and Epithelial Cytokeratins in Diverse Human and Bovine Tissues (Hair Follicle, Nail Bed and Matrix, Lingual Papilla, Thymic Reticulum) Differentiation · 1988
    9. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues: Human and Bovine Hair Follicles Differentiation · 1988
    10. Collagen-Type Synthesis in Human Hair Papilla Cells in Culture Archives of Dermatological Research · 1988
    11. The Dermal Papilla and Maintenance of Hair Growth 1988
    12. Studies of Developing Human Hair Shaft Cells In Vitro Journal of Investigative Dermatology · 1988
    13. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987
    14. Growth of Human Hair Follicle Keratinocytes In Vitro Journal of the American Academy of Dermatology · 1987
    15. Organotypic Culture of Outer Root Sheath Cells from Human Hair Follicles Using a New Culture Device In Vitro Cellular & Developmental Biology - Plant · 1987
    16. Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    17. The In Vitro Properties of Dermal Papilla Cell Lines Established From Human Hair Follicles British Journal of Dermatology · 1986
    18. Hair, Wool, Quill, Nail, Claw, Hoof, and Horn 1986
    19. A Method for Culturing Human Hair Follicle Cells British Journal of Dermatology · 1981

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    4. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994