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Glossary Stratified Epithelium

Stratified epithelium is a type of tissue composed of multiple layers of cells, providing a protective barrier in various parts of the body, including the skin and mucous membranes. In the context of hair biology, stratified epithelium is relevant as it forms the outer layer of the hair follicle, contributing to the structural integrity and health of hair. Key distinguishing characteristics include its ability to regenerate quickly and its role in protecting underlying tissues from mechanical stress, pathogens, and dehydration.

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research Keratin 15 Expression in Stratified Epithelia: Downregulation in Activated Keratinocytes

198 citations , March 1999 in “Journal of Investigative Dermatology”

This study found that keratin 15 expression is downregulated in hyperproliferative conditions like psoriasis and hypertrophic scars, suggesting it is not compatible with keratinocyte activation.

research Defining a Region of the Human Keratin 6a Gene That Confers Inducible Expression in Stratified Epithelia of Transgenic Mice

44 citations , May 1997 in “Journal of Biological Chemistry”

This study found that regulatory sequences crucial for inducing K6a expression in response to epidermal injury are located in specific upstream regions of the K6a gene in transgenic mice.