A Prospective Self-Controlled Clinical Trial of Nonactivated Low Leukocyte PRP in Female Pattern Hair Loss Patients of Childbearing Age

May 2024 in “ Dermatologic surgery ”

Peng Xue-bing, S. Li, X Zhou, Kexin Zhu, Xiangrong Ni, Xiang-Dong Qi

female pattern hair loss alopecia subcutaneous scalp injections nonactivated low leukocyte platelet-rich plasma PRP hair density hair follicle density local swelling pain scalp injections platelet-rich plasma swelling

Studysummary In this study involving 15 women with alopecia, subcutaneous scalp injections of platelet-rich plasma every four weeks for three sessions led to increased hair and hair follicle density at 24 weeks, with common side effects being local swelling and pain. Our plain-language summary of this paper — not a Tressless recommendation.

A prospective self-controlled clinical trial involving 15 female patients of childbearing age with alopecia evaluated the efficacy of subcutaneous scalp injections of nonactivated low leukocyte platelet-rich plasma (PRP). Patients received PRP injections every 4 weeks for a total of 3 treatments. Results showed a significant increase in hair density from 151 ± 39.82 hairs/cm² to 170.96 ± 37.14 hairs/cm² and hair follicle density from 151.04 ± 41.99 follicles/cm² to 166.72 ± 37.13 follicles/cm² at the 24-week follow-up. The primary adverse reactions were local swelling and pain. The study concluded that nonactivated low leukocyte PRP could be an effective treatment for alleviating alopecia symptoms in female patients.

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