Recent Omics Advances In Hair Aging Biology And Hair Biomarkers Analysis

    August 2023 in “ Ageing Research Reviews ”
    Sunil S. Adav, Kee Woei Ng
    Studysummary More research is needed to understand hair aging and develop effective treatments.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 110

    1. Hair Follicles as a Critical Model for Monitoring the Circadian Clock International Journal of Molecular Sciences · 2023
    2. Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness eLife · 2022
    3. Single-Cell Transcriptomics Reveals Lineage Trajectory of Human Scalp Hair Follicle and Informs Mechanisms of Hair Graying Cell discovery · 2022
    4. A Systematic Review on the Lipid Composition of Human Hair International Journal of Dermatology · 2022
    5. Prevalence of Early-Onset Androgenetic Alopecia and Its Relation with Lifestyle and Dietary Habits Italian journal of dermatology and venereology · 2022
    6. Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging Frontiers in Cell and Developmental Biology · 2021
    7. Hair Growth Stimulation Effect of Centipeda Minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways Biomolecules · 2021
    8. Love Is in the Hair: Arginine Methylation of Human Hair Proteins as Novel Cardiovascular Biomarkers Amino acids · 2021
    9. mTORC1 Activity Controls Human Scalp Hair Follicle Pigmentation and Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2021
    10. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    11. Telomere Dynamics and Telomerase in the Biology of Hair Follicles and Their Stem Cells as a Model for Aging Research Journal of Investigative Dermatology · 2021
    12. Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation Journal of Investigative Dermatology · 2021
    13. Transcriptome Profiling of Human Follicle Dermal Papilla Cells in Response to Porphyra-334 Treatment by RNA-Seq Evidence-based complementary and alternative medicine · 2021
    14. Self-Assembly of Solubilized Human Hair Keratins ACS biomaterials science & engineering · 2020
    15. Age-Related Changes in Female Scalp Dermal Sheath and Dermal Fibroblasts: How the Hair Follicle Environment Impacts Hair Aging Journal of Investigative Dermatology · 2020
    16. Stress-Sensing in the Human Greying Hair Follicle: Ataxia Telangiectasia Mutated (ATM) Depletion in Hair Bulb Melanocytes in Canities-Prone Scalp Scientific reports · 2020
    17. Towards Best Practice in Hair Metabolomic Studies: Systematic Investigation on the Impact of Hair Length and Color Metabolites · 2020
    18. Discrete Nanoscale Distribution of Hair Lipids Fails to Provide Humidity Resistance Analytical chemistry · 2020
    19. Exploring the Possibility of Predicting Human Head Hair Greying from DNA Using Whole-Exome and Targeted NGS Data BMC Genomics · 2020
    20. Exploration of Potential Lipid Biomarkers for Premature Canities by UPLC-QTOF-MS Analyses of Hair Follicle Roots Experimental dermatology · 2020
    21. Age-Related Changes in Hair Shaft Protein Profiling and Genetically Variant Peptides Forensic Science International Genetics · 2020
    22. Proteomic Characterization of Damaged Single Hairs Recovered After an Explosion for Protein-Based Human Identification Journal of proteome research · 2020
    23. Potential Use of Human Hair Shaft Keratin Peptide Signatures to Distinguish Gender and Ethnicity PeerJ · 2020
    24. Hyperactivation of Sympathetic Nerves Drives Depletion of Melanocyte Stem Cells Nature · 2020
    25. Cheating on Forensic Hair Testing? Detection of Potential Biomarkers for Cosmetically Altered Hair Samples Using Untargeted Hair Metabolomics Analyst · 2020
    26. Human Pollution Exposure Correlates With Accelerated Ultrastructural Degradation of Hair Fibers Proceedings of the National Academy of Sciences of the United States of America · 2019
    27. Known and Unknown Features of Hair Cuticle Structure: A Brief Review Cosmetics · 2019
    28. Degradation of Hair Surface: Importance of 18-MEA and Epicuticle Cosmetics · 2019
    29. Histopathology of Aging of the Hair Follicle Journal of Cutaneous Pathology · 2019
    30. Lipid Losses and Barrier Function Modifications of the Brown-to-White Hair Transition Skin research and technology · 2019
    31. Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine International Journal of Cosmetic Science · 2019
    32. Human Hair as a Testing Substrate in the Era of Precision Medicine: Potential Role of Omics-Based Approaches IntechOpen eBooks · 2018
    33. A Study on Photostability of Ethyl Glucuronide in Hair Irradiated Under Artificial Sunlight Journal of Analytical Toxicology · 2018
    34. Eccrine Sweat Glands Associate With the Human Hair Follicle Within a Defined Compartment of Dermal White Adipose Tissue British Journal of Dermatology · 2018
    35. Melatonin: A Cutaneous Perspective on Its Production, Metabolism, and Functions Journal of Investigative Dermatology · 2018
    36. Studies on the Proteome of Human Hair: Identification of Histones and Deamidated Keratins Scientific reports · 2018
    37. Scalp Condition Impacts Hair Growth And Retention Via Oxidative Stress International journal of trichology · 2018
    38. Anatomy and Physiology of Hair InTech eBooks · 2017
    39. Exogenous and Endogenous Lipids of Human Hair Skin research and technology · 2017
    40. iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration PLOS ONE · 2016
    41. Metabolomic Analysis of Amino Acids and Lipids in Human Hair Altered by Dyeing, Perming, and Bleaching Experimental Dermatology · 2016
    42. A Genome-Wide Association Scan in Admixed Latin Americans Identifies Loci Influencing Facial and Scalp Hair Features Nature Communications · 2016
    43. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
    44. The Impact of Oxidative Stress on Hair International Journal of Cosmetic Science · 2015
    45. LC-MS/MS-Based Method for Long-Term Steroid Profiling in Human Scalp Hair Clinical Endocrinology · 2015
    46. Age-Related Hair Pigment Loss Current problems in dermatology · 2015
    47. Understanding Hair Loss Due to Air Pollution and the Approach to Management Hair therapy & transplantation · 2015
    48. Epidermal Stem Cells and Skin Tissue Engineering in Hair Follicle Regeneration World Journal of Stem Cells · 2015
    49. Association of Premature Hair Graying with Family History, Smoking, and Obesity: A Cross-Sectional Study Journal of The American Academy of Dermatology · 2014
    50. The Peripheral Clock Regulates Human Pigmentation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2014
    51. Human Hair Shaft Proteomic Profiling: Individual Differences, Site Specificity, And Cuticle Analysis PeerJ · 2014
    52. Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives Trends in Molecular Medicine · 2014
    53. Premature Graying as a Consequence of Compromised Antioxidant Activity in Hair Bulb Melanocytes and Their Precursors PLOS ONE · 2014
    54. Regenerative Hair Waves in Aging Mice and Extra-Follicular Modulators Follistatin, Dkk1, and Sfrp4 Journal of Investigative Dermatology · 2014
    55. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    56. A Review of Adipocyte Lineage Cells and Dermal Papilla Cells in Hair Follicle Regeneration Journal of Tissue Engineering · 2014
    57. Phototrichogram Analysis of Normal Scalp Hair Characteristics with Aging European Journal of Dermatology · 2013
    58. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    59. A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock Journal of Investigative Dermatology · 2013
    60. Age-Induced Hair Greying: The Multiple Effects of Oxidative Stress International Journal of Cosmetic Science · 2013
    61. Keratins and Lipids in Ethnic Hair International Journal of Cosmetic Science · 2013
    62. The Ethnic Differences in Hair Damage and Integral Hair Lipid After Ultraviolet Radiation Annals of Dermatology · 2013
    63. Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia BioMed Research International · 2013
    64. Characteristic Features of Ageing in Korean Women's Hair and Scalp British Journal of Dermatology · 2012
    65. The Proteomic Profile of Hair Damage British Journal of Dermatology · 2012
    66. Comparative Secretome Analysis of Human Follicular Dermal Papilla Cells and Fibroblasts Using Shotgun Proteomics BMB Reports · 2012
    67. What Women Want: Quantifying the Perception of Hair Amount - An Analysis of Hair Diameter and Density Changes with Age in Caucasian Women British Journal of Dermatology · 2012
    68. Identification of Breast Cancer-Associated Lipids in Scalp Hair Breast cancer · 2012
    69. Assessment of Hair Density and Caliber in Caucasian and Asian Female Subjects with Female Pattern Hair Loss Using the Folliscope Journal of The American Academy of Dermatology · 2011
    70. Investigation by Imaging Mass Spectrometry of Biomarker Candidates for Aging in the Hair Cortex PloS one · 2011
    71. Proteomic Tools for the Investigation of Human Hair Structural Proteins and Evidence of Weakness Sites on Hair Keratin Coil Segments Analytical biochemistry · 2011
    72. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    73. The Secretory Clear Cell of the Eccrine Sweat Gland as the Probable Source of Excess Sweat Production in Hyperhidrosis Experimental Dermatology · 2011
    74. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    75. The Use of Polyethylenimine–DNA to Topically Deliver hTERT to Promote Hair Growth Gene Therapy · 2011
    76. Aging Processes Influence Keratin and KAP Expression in Human Hair Follicles Experimental Dermatology · 2011
    77. Proteomics Demonstration That Histone H4 Is a Colchicine-Induced Retro-Modulator of Growth and Alkaline Phosphatase Activity in Hair Follicle Dermal Papilla Culture Journal of proteomics · 2011
    78. Human Hair Follicle and Epidermal Melanocytes Exhibit Striking Differences in Their Aging Profile Involving Catalase ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    79. A Neuroendocrinological Perspective on Human Hair Follicle Pigmentation Pigment Cell & Melanoma Research · 2010
    80. Chronological Aging of Human Hair Keratin Fibers International Journal of Cosmetic Science · 2010
    81. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    82. Senile Hair Graying: H2O2-Mediated Oxidative Stress Affects Human Hair Color by Blunting Methionine Sulfoxide Repair The FASEB Journal · 2009
    83. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    84. Aging of the Hair Follicle Pigmentation System International journal of trichology · 2009
    85. Characterization and Expression Analysis of the Hair Keratin Associated Protein KAP26.1 British Journal of Dermatology · 2008
    86. Melatonin and the Hair Follicle Journal of pineal research · 2007
    87. Measurement of Cortisol in Human Hair as a Biomarker of Systemic Exposure Clinical and investigative medicine · 2007
    88. Towards A Free Radical Theory Of Graying: Melanocyte Apoptosis In The Aging Human Hair Follicle As An Indicator Of Oxidative Stress Induced Tissue Damage ˜The œFASEB journal · 2006
    89. Proteome Analysis of Human Hair Shaft Molecular & Cellular Proteomics · 2006
    90. Changes in Different Melanocyte Populations During Hair Follicle Involution (Catagen) ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    91. Hair Melanocytes as Neuro-Endocrine Sensors—Pigments for Our Imagination Molecular and cellular endocrinology · 2005
    92. Diversity of Hair Growth Profiles International Journal of Dermatology · 2005
    93. Size Polymorphisms in the Human Ultrahigh Sulfur Hair Keratin-Associated Protein 4, KAP4, Gene Family ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    94. Melanocyte Stem Cell Maintenance and Hair Graying Cell · 2005
    95. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    96. Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    97. Macrophage-Stimulating Protein Promotes Hair Growth Ex Vivo and Induces Anagen from Telogen Stage Hair Follicles In Vivo Journal of Investigative Dermatology · 2004
    98. Hair Cycle and Hair Pigmentation: Dynamic Interactions and Changes Associated with Aging Micron · 2003
    99. Thrombospondin-1 Plays a Critical Role in the Induction of Hair Follicle Involution and Vascular Regression During the Catagen Phase Journal of Investigative Dermatology · 2003
    100. Association Between Smoking and Hair Loss: Another Opportunity for Health Education Against Smoking? Dermatology · 2003
    101. Defolliculated (Dfl): A Dominant Mouse Mutation Leading to Poor Sebaceous Gland Differentiation and Total Elimination of Pelage Follicles Journal of Investigative Dermatology · 2002
    102. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    103. Melanocyte Subpopulation Turnover During the Human Hair Cycle: An Immunohistochemical Study Pigment cell research · 2000
    104. Androgenetic Alopecia and Microinflammation International Journal of Dermatology · 2000
    105. Three-Dimensional Microanatomy of Longitudinal Lanceolate Endings in Rat Vibrissae Journal of comparative neurology · 2000
    106. EEMCO Guidance for the In Vivo Assessment of Skin Greasiness Skin Pharmacology and Physiology · 2000
    107. Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999
    108. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    109. Influence of Pigmentation on the Codeine Content of Hair Fibers in Guinea Pigs Journal of Forensic Sciences · 1997
    110. Hair: Its Structure and Response to Cosmetic Preparations Clinics in dermatology · 1996

    Related research 5

    1. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    2. Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases in the Hair Cycle Experimental and Therapeutic Medicine · 2016
    3. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    4. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    5. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006