Recent Omics Advances In Hair Aging Biology And Hair Biomarkers Analysis

August 2023 in “ Ageing Research Reviews ”

Sunil S. Adav, Kee Woei Ng

omics technologies hair aging hair thinning hair loss hair graying hair proteome hair metabolome genetics UV radiation pollution genomics proteomics metabolomics clinical biomarkers

TLDR More research is needed to understand hair aging and develop effective treatments.

The review discusses recent advances in "omics" technologies and their application in understanding hair aging, focusing on hair thinning, loss, and graying. It highlights the complexity of hair proteome and metabolome and the impact of intrinsic factors like genetics and extrinsic factors such as UV radiation and pollution on hair aging. The study emphasizes the potential of integrated omics platforms, including genomics, proteomics, and metabolomics, to provide insights into age-associated changes in hair and identify new clinical biomarkers. Despite progress, the mechanisms of hair aging remain poorly understood, and the review calls for further research to develop effective hair therapies.

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