Recent Omics Advances In Hair Aging Biology And Hair Biomarkers Analysis

    August 2023 in “ Ageing Research Reviews ”
    Sunil S. Adav, Kee Woei Ng
    Studysummary More research is needed to understand hair aging and develop effective treatments.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 112

    1. Hair Follicles as a Critical Model for Monitoring the Circadian Clock International Journal of Molecular Sciences · 2023
    2. Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness eLife · 2022
    3. Understanding Mammalian Hair Follicle Ecosystems by Single-Cell RNA Sequencing Animals · 2022
    4. Single-Cell Transcriptomics Reveals Lineage Trajectory of Human Scalp Hair Follicle and Informs Mechanisms of Hair Graying Cell discovery · 2022
    5. A Systematic Review on the Lipid Composition of Human Hair International Journal of Dermatology · 2022
    6. Prevalence of Early-Onset Androgenetic Alopecia and Its Relation with Lifestyle and Dietary Habits Italian journal of dermatology and venereology · 2022
    7. Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging Frontiers in Cell and Developmental Biology · 2021
    8. Hair Growth Stimulation Effect of Centipeda Minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways Biomolecules · 2021
    9. Love Is in the Hair: Arginine Methylation of Human Hair Proteins as Novel Cardiovascular Biomarkers Amino acids · 2021
    10. mTORC1 Activity Controls Human Scalp Hair Follicle Pigmentation and Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2021
    11. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    12. Telomere Dynamics and Telomerase in the Biology of Hair Follicles and Their Stem Cells as a Model for Aging Research Journal of Investigative Dermatology · 2021
    13. Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation Journal of Investigative Dermatology · 2021
    14. Transcriptome Profiling of Human Follicle Dermal Papilla Cells in Response to Porphyra-334 Treatment by RNA-Seq Evidence-based complementary and alternative medicine · 2021
    15. Self-Assembly of Solubilized Human Hair Keratins ACS biomaterials science & engineering · 2020
    16. Age-Related Changes in Female Scalp Dermal Sheath and Dermal Fibroblasts: How the Hair Follicle Environment Impacts Hair Aging Journal of Investigative Dermatology · 2020
    17. Stress-Sensing in the Human Greying Hair Follicle: Ataxia Telangiectasia Mutated (ATM) Depletion in Hair Bulb Melanocytes in Canities-Prone Scalp Scientific reports · 2020
    18. Towards Best Practice in Hair Metabolomic Studies: Systematic Investigation on the Impact of Hair Length and Color Metabolites · 2020
    19. The biology of human hair greying Biological reviews/Biological reviews of the Cambridge Philosophical Society · 2020
    20. Discrete Nanoscale Distribution of Hair Lipids Fails to Provide Humidity Resistance Analytical chemistry · 2020
    21. Exploring the Possibility of Predicting Human Head Hair Greying from DNA Using Whole-Exome and Targeted NGS Data BMC Genomics · 2020
    22. Exploration of Potential Lipid Biomarkers for Premature Canities by UPLC-QTOF-MS Analyses of Hair Follicle Roots Experimental dermatology · 2020
    23. Age-Related Changes in Hair Shaft Protein Profiling and Genetically Variant Peptides Forensic Science International Genetics · 2020
    24. Proteomic Characterization of Damaged Single Hairs Recovered After an Explosion for Protein-Based Human Identification Journal of proteome research · 2020
    25. Potential Use of Human Hair Shaft Keratin Peptide Signatures to Distinguish Gender and Ethnicity PeerJ · 2020
    26. Hyperactivation of Sympathetic Nerves Drives Depletion of Melanocyte Stem Cells Nature · 2020
    27. Cheating on Forensic Hair Testing? Detection of Potential Biomarkers for Cosmetically Altered Hair Samples Using Untargeted Hair Metabolomics Analyst · 2020
    28. Human Pollution Exposure Correlates With Accelerated Ultrastructural Degradation of Hair Fibers Proceedings of the National Academy of Sciences of the United States of America · 2019
    29. Known and Unknown Features of Hair Cuticle Structure: A Brief Review Cosmetics · 2019
    30. Degradation of Hair Surface: Importance of 18-MEA and Epicuticle Cosmetics · 2019
    31. Histopathology of Aging of the Hair Follicle Journal of Cutaneous Pathology · 2019
    32. Lipid Losses and Barrier Function Modifications of the Brown-to-White Hair Transition Skin research and technology · 2019
    33. Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine International Journal of Cosmetic Science · 2019
    34. Human Hair as a Testing Substrate in the Era of Precision Medicine: Potential Role of Omics-Based Approaches IntechOpen eBooks · 2018
    35. A Study on Photostability of Ethyl Glucuronide in Hair Irradiated Under Artificial Sunlight Journal of Analytical Toxicology · 2018
    36. Eccrine Sweat Glands Associate With the Human Hair Follicle Within a Defined Compartment of Dermal White Adipose Tissue British Journal of Dermatology · 2018
    37. Melatonin: A Cutaneous Perspective on Its Production, Metabolism, and Functions Journal of Investigative Dermatology · 2018
    38. Studies on the Proteome of Human Hair: Identification of Histones and Deamidated Keratins Scientific reports · 2018
    39. Scalp Condition Impacts Hair Growth And Retention Via Oxidative Stress International journal of trichology · 2018
    40. Anatomy and Physiology of Hair InTech eBooks · 2017
    41. Exogenous and Endogenous Lipids of Human Hair Skin research and technology · 2017
    42. iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration PLOS ONE · 2016
    43. Metabolomic Analysis of Amino Acids and Lipids in Human Hair Altered by Dyeing, Perming, and Bleaching Experimental Dermatology · 2016
    44. A Genome-Wide Association Scan in Admixed Latin Americans Identifies Loci Influencing Facial and Scalp Hair Features Nature Communications · 2016
    45. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
    46. The Impact of Oxidative Stress on Hair International Journal of Cosmetic Science · 2015
    47. LC-MS/MS-Based Method for Long-Term Steroid Profiling in Human Scalp Hair Clinical Endocrinology · 2015
    48. Age-Related Hair Pigment Loss Current problems in dermatology · 2015
    49. Understanding Hair Loss Due to Air Pollution and the Approach to Management Hair therapy & transplantation · 2015
    50. Epidermal Stem Cells and Skin Tissue Engineering in Hair Follicle Regeneration World Journal of Stem Cells · 2015
    51. Association of Premature Hair Graying with Family History, Smoking, and Obesity: A Cross-Sectional Study Journal of The American Academy of Dermatology · 2014
    52. The Peripheral Clock Regulates Human Pigmentation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2014
    53. Human Hair Shaft Proteomic Profiling: Individual Differences, Site Specificity, And Cuticle Analysis PeerJ · 2014
    54. Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives Trends in Molecular Medicine · 2014
    55. Premature Graying as a Consequence of Compromised Antioxidant Activity in Hair Bulb Melanocytes and Their Precursors PLOS ONE · 2014
    56. Regenerative Hair Waves in Aging Mice and Extra-Follicular Modulators Follistatin, Dkk1, and Sfrp4 Journal of Investigative Dermatology · 2014
    57. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    58. A Review of Adipocyte Lineage Cells and Dermal Papilla Cells in Hair Follicle Regeneration Journal of Tissue Engineering · 2014
    59. Phototrichogram Analysis of Normal Scalp Hair Characteristics with Aging European Journal of Dermatology · 2013
    60. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    61. A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock Journal of Investigative Dermatology · 2013
    62. Age-Induced Hair Greying: The Multiple Effects of Oxidative Stress International Journal of Cosmetic Science · 2013
    63. Keratins and Lipids in Ethnic Hair International Journal of Cosmetic Science · 2013
    64. The Ethnic Differences in Hair Damage and Integral Hair Lipid After Ultraviolet Radiation Annals of Dermatology · 2013
    65. Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia BioMed Research International · 2013
    66. Characteristic Features of Ageing in Korean Women's Hair and Scalp British Journal of Dermatology · 2012
    67. The Proteomic Profile of Hair Damage British Journal of Dermatology · 2012
    68. Comparative Secretome Analysis of Human Follicular Dermal Papilla Cells and Fibroblasts Using Shotgun Proteomics BMB Reports · 2012
    69. What Women Want: Quantifying the Perception of Hair Amount - An Analysis of Hair Diameter and Density Changes with Age in Caucasian Women British Journal of Dermatology · 2012
    70. Identification of Breast Cancer-Associated Lipids in Scalp Hair Breast cancer · 2012
    71. Assessment of Hair Density and Caliber in Caucasian and Asian Female Subjects with Female Pattern Hair Loss Using the Folliscope Journal of The American Academy of Dermatology · 2011
    72. Investigation by Imaging Mass Spectrometry of Biomarker Candidates for Aging in the Hair Cortex PloS one · 2011
    73. Proteomic Tools for the Investigation of Human Hair Structural Proteins and Evidence of Weakness Sites on Hair Keratin Coil Segments Analytical biochemistry · 2011
    74. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    75. The Secretory Clear Cell of the Eccrine Sweat Gland as the Probable Source of Excess Sweat Production in Hyperhidrosis Experimental Dermatology · 2011
    76. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    77. The Use of Polyethylenimine–DNA to Topically Deliver hTERT to Promote Hair Growth Gene Therapy · 2011
    78. Aging Processes Influence Keratin and KAP Expression in Human Hair Follicles Experimental Dermatology · 2011
    79. Proteomics Demonstration That Histone H4 Is a Colchicine-Induced Retro-Modulator of Growth and Alkaline Phosphatase Activity in Hair Follicle Dermal Papilla Culture Journal of proteomics · 2011
    80. Human Hair Follicle and Epidermal Melanocytes Exhibit Striking Differences in Their Aging Profile Involving Catalase ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    81. A Neuroendocrinological Perspective on Human Hair Follicle Pigmentation Pigment Cell & Melanoma Research · 2010
    82. Chronological Aging of Human Hair Keratin Fibers International Journal of Cosmetic Science · 2010
    83. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    84. Senile Hair Graying: H2O2-Mediated Oxidative Stress Affects Human Hair Color by Blunting Methionine Sulfoxide Repair The FASEB Journal · 2009
    85. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    86. Aging of the Hair Follicle Pigmentation System International journal of trichology · 2009
    87. Characterization and Expression Analysis of the Hair Keratin Associated Protein KAP26.1 British Journal of Dermatology · 2008
    88. Melatonin and the Hair Follicle Journal of pineal research · 2007
    89. Measurement of Cortisol in Human Hair as a Biomarker of Systemic Exposure Clinical and investigative medicine · 2007
    90. Towards A Free Radical Theory Of Graying: Melanocyte Apoptosis In The Aging Human Hair Follicle As An Indicator Of Oxidative Stress Induced Tissue Damage ˜The œFASEB journal · 2006
    91. Proteome Analysis of Human Hair Shaft Molecular & Cellular Proteomics · 2006
    92. Changes in Different Melanocyte Populations During Hair Follicle Involution (Catagen) ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    93. Hair Melanocytes as Neuro-Endocrine Sensors—Pigments for Our Imagination Molecular and cellular endocrinology · 2005
    94. Diversity of Hair Growth Profiles International Journal of Dermatology · 2005
    95. Size Polymorphisms in the Human Ultrahigh Sulfur Hair Keratin-Associated Protein 4, KAP4, Gene Family ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    96. Melanocyte Stem Cell Maintenance and Hair Graying Cell · 2005
    97. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    98. Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    99. Macrophage-Stimulating Protein Promotes Hair Growth Ex Vivo and Induces Anagen from Telogen Stage Hair Follicles In Vivo Journal of Investigative Dermatology · 2004
    100. Hair Cycle and Hair Pigmentation: Dynamic Interactions and Changes Associated with Aging Micron · 2003
    101. Thrombospondin-1 Plays a Critical Role in the Induction of Hair Follicle Involution and Vascular Regression During the Catagen Phase Journal of Investigative Dermatology · 2003
    102. Association Between Smoking and Hair Loss: Another Opportunity for Health Education Against Smoking? Dermatology · 2003
    103. Defolliculated (Dfl): A Dominant Mouse Mutation Leading to Poor Sebaceous Gland Differentiation and Total Elimination of Pelage Follicles Journal of Investigative Dermatology · 2002
    104. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    105. Melanocyte Subpopulation Turnover During the Human Hair Cycle: An Immunohistochemical Study Pigment cell research · 2000
    106. Androgenetic Alopecia and Microinflammation International Journal of Dermatology · 2000
    107. Three-Dimensional Microanatomy of Longitudinal Lanceolate Endings in Rat Vibrissae Journal of comparative neurology · 2000
    108. EEMCO Guidance for the In Vivo Assessment of Skin Greasiness Skin Pharmacology and Physiology · 2000
    109. Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999
    110. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    111. Influence of Pigmentation on the Codeine Content of Hair Fibers in Guinea Pigs Journal of Forensic Sciences · 1997
    112. Hair: Its Structure and Response to Cosmetic Preparations Clinics in dermatology · 1996

    Related research 5

    1. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    2. Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases in the Hair Cycle Experimental and Therapeutic Medicine · 2016
    3. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    4. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    5. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006