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GlossaryProteomics

large-scale study of proteins in biological systems

Proteomics is the large-scale study of proteins, which are vital parts of living organisms and perform a variety of functions within cells. It involves identifying and quantifying proteins, understanding their structures and functions, and how they interact within a biological system. This field is crucial for understanding diseases, including those affecting hair and skin, such as alopecia, by revealing changes in protein expression and function.

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research Differential Proteomics of Lesional vs. Non-Lesional Biopsies Revealed Non-Immune Mechanisms of Alopecia Areata

19 citations , January 2018 in “Scientific Reports”

Non-immune factors play a significant role in alopecia areata.

research Emerging Diagnostic and Therapeutic Potentials of Human Hair Proteomics

14 citations , September 2017 in “Proteomics. Clinical applications”

Hair protein analysis could improve medical testing and understanding of hair characteristics.

research Differential Expression of Proteins Associated with the Hair Follicle Cycle: Proteomics and Bioinformatics Analyses

10 citations , January 2016 in “PLOS ONE”

Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.

research Proteomics Analysis of the Secondary Hair Follicle Cycle in Liaoning Cashmere Goat

5 citations , May 2021 in “Small ruminant research”

The study found specific proteins that could mark different growth stages of cashmere goat hair and may help improve cashmere production.

research Proteomics Demonstration That Histone H4 Is a Colchicine-Induced Retro-Modulator of Growth and Alkaline Phosphatase Activity in Hair Follicle Dermal Papilla Culture

5 citations , March 2011 in “Journal of proteomics”

Histone H4, released by cells exposed to colchicine, can cause hair loss by inhibiting cell growth and enzyme activity.

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in Chat 237 upvotes 10 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

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in Progress Pictures 135 upvotes 2 years ago

The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hair growth. Another user reassured them that vaping wouldn't affect their progress.

community Bruteforcing alopecia or the new advent of science progress

in Research/Science 21 upvotes 8 months ago

Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.

community I'm becoming non-responder to minoxidil. What's going on?

in Minoxidil 6 upvotes 1 month ago

The user experienced reduced effectiveness of minoxidil after consistent use, despite using dutasteride to maintain hair. They are considering alternatives like microneedling and exploring options like hair transplants due to dissatisfaction with current hair density.