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Glossary Proteomics

large-scale study of proteins in biological systems

Proteomics is the large-scale study of proteins, which are vital parts of living organisms and perform a variety of functions within cells. It involves identifying and quantifying proteins, understanding their structures and functions, and how they interact within a biological system. This field is crucial for understanding diseases, including those affecting hair and skin, such as alopecia, by revealing changes in protein expression and function.

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research Proteomic analysis of human mesenchymal stromal cell secretomes: a systematic comparison of the angiogenic potential

187 citations , April 2019 in “npj Regenerative Medicine”

This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.

research The proteomics of keratin proteins

62 citations , August 2006 in “Journal of Chromatography B”

This article reviews the challenges in studying keratin proteins and emphasizes the potential of modern proteomic techniques to advance their research, but it reports no new findings.

research Bioengineering a humanized acne microenvironment model: Proteomics analysis of host responses to Propionibacterium acnes infection in vivo

40 citations , July 2008 in “PROTEOMICS”

This study introduced a bioengineered model that simulates acne's microenvironment in mice, enabling the exploration of host and P. acnes interactions and presenting a novel platform for anti-acne drug and vaccine screening.

Proteomic Tools for the Investigation of Human Hair Structural Proteins and Evidence of Weakness Sites on Hair Keratin Coil Segments

research Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments

38 citations , October 2011 in “Analytical biochemistry”

This study used proteomic techniques to analyze human hair proteins, revealing keratin heterogeneity and identifying posttranslational modifications, such as cysteine trioxidation and methylation.

research Distinguishing Mouse Strains by Proteomic Analysis of Pelage Hair

34 citations , March 2009 in “Journal of Investigative Dermatology”

Proteomic analysis can identify genetic differences in mouse hair, helping understand hair defects and variations.

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