Potential Use of Human Hair Shaft Keratin Peptide Signatures to Distinguish Gender and Ethnicity

    January 2020 in “ PeerJ ”
    Nurdiena Nasir, Jumriah Hiji, Jaime Jacqueline Jayapalan, Onn Haji Hashim
    TLDR Keratin peptides in hair might help identify gender and ethnicity.
    The study investigated the potential of using human hair shaft keratin peptide signatures to distinguish gender and ethnicity, involving 40 individuals of different ethnicities. Researchers identified significant differences in the abundance of specific keratins between genders and among Malaysian ethnic groups, with keratin types K81, K85, and K86 varying significantly between genders, and K33b, K81, K83, and K86 differing among ethnicities. Indian female subjects showed the highest mean percentage of volume contribution for certain protein spots. The study suggested that hair shaft protein profiles could serve as biomarkers for gender and ethnicity identification, but emphasized the need for larger-scale analyses and consideration of external factors to confirm these findings for forensic applications.
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