Development of High-Performance Two-Dimensional Gel Electrophoresis for Human Hair Shaft Proteome

    March 2019 in “ PLoS ONE ”
    Sing Ying Wong, Onn Haji Hashim, Nobuhiro Hayashi
    Studysummary In this study, the authors developed a modified alkaline-based proteomics protocol that improved the reproducibility of detecting hair proteins, potentially aiding future biomarker discovery.
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    Research cited in this study 8

    1. Characterization of the Promoter Regions of Two Sheep Keratin-Associated Protein Genes for Hair Cortex-Specific Expression PloS one · 2016
    2. Human Hair Shaft Proteomic Profiling: Individual Differences, Site Specificity, And Cuticle Analysis PeerJ · 2014
    3. A Novel Purification Procedure for Keratin-Associated Proteins and Keratin from Human Hair Journal of Biological Macromolecules · 2013
    4. Proteome Analysis of Human Hair Shaft Molecular & Cellular Proteomics · 2006
    5. Apoptosis and Keratin Intermediate Filaments Cell Death and Differentiation · 2002
    6. A Rapid Extraction Procedure of Human Hair Proteins and Identification of Phosphorylated Species Biological and Pharmaceutical Bulletin · 2002
    7. The Role of Keratin Proteins and Their Genes in the Growth, Structure, and Properties of Hair Birkhäuser Basel eBooks · 1997
    8. Sequence, Expression, and Evolutionary Conservation of a Gene Encoding a Glycine/Tyrosine-Rich Keratin-Associated Protein of Hair Journal of Biological Chemistry · 1993

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    1. Potential Use of Human Hair Shaft Keratin Peptide Signatures to Distinguish Gender and Ethnicity PeerJ · 2020