Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia

    January 2013 in “ BioMed Research International ”
    Piérard-Franchimont C, G. Loussouarn, S. Panhard, Didier Saint Léger, Myriam Mellul, Gérald Pierard
    Image of study
    TLDR Age, gender, and hair loss affect scalp characteristics differently in young Caucasian adults.
    The study conducted on 650 Caucasian volunteers (300 women and 350 men) over 7 years examined the effects of age, gender, and alopecia on the interfollicular scalp. It found significant gender differences in young adults without alopecia, with men showing more solar elastosis, dermal cellularity, and dermal dendrocytes, while women had a more developed microvasculature. Ageing led to increased solar elastosis and decreased epidermal proliferation and dermal cellularity in both genders. Alopecia in young adults was linked to an increase in versican+ stromal cells and lymphatic vessels in men, and increased lysozyme deposits in women. The study concluded that alopecia may mimic stress-induced premature senescence and highlighted a strong gender effect on the scalp in young adults.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 1000+ results

      community Anyone here going the “natural” route?

      in Scalp Massage  48 upvotes 2 years ago
      People discussing their experiences with natural treatments for hair loss, such as essential oils, deep scalp massages, anti-inflammatory measures, and supplements. Most of the replies suggest that these treatments are not effective and recommend medication such as minoxidil or finasteride instead.

      community 7 Month Hair Progress (0.5 mg dut only, diffuse thinning)

      in Progress Pictures  714 upvotes 8 months ago
      An 18-year-old male switched from topical finasteride and minoxidil to oral dutasteride for diffuse hair loss and saw improvement without side effects, despite experiencing scalp itch and shedding. Commenters noted significant hair regrowth and were surprised by his young age and appearance.

      community Nothing's working, I feel depressed, also hopeless for the first time

      in Update  102 upvotes 2 years ago
      A user's experience with hair loss treatments, including Finasteride, Minoxidil, Nizoral Shampoo, Rosemary Oil, Vitamin D, Biotin, Vitamin C, Zinc and Dermarolling, that have not been successful over the past 14 months. Other users gave advice on how to cope with the issue, such as exercising, changing mindset, and shaving their head.

      community Are they going to Ban Finasteride in the EU ?

      in Finasteride/Dutasteride  68 upvotes 1 month ago
      There is concern about a potential ban on finasteride in the EU, but many believe it is unlikely unless serious side effects are found. Users rely on finasteride for hair loss and other health benefits, and a petition has been created to oppose any restrictions.

      community 2 months update, experiencing massive gains

      in Progress Pictures  444 upvotes 10 months ago
      A user reports significant hair regrowth after 2 months using Minoxidil, Finasteride, oiling, derma rolling, and taking multivitamins, omega 3, and vitamin D. Some users discuss the frequency of derma rolling, with varying practices ranging from once every two weeks to four times a week.

      community Alopecia Areata Question

      in Treatment  2 upvotes 3 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

    Similar Research

    5 / 1000+ results