Revisiting Dandruff: Role of Malassezia Yeasts and Treatment Implications

    September 2006 in “ International Journal of Cosmetic Science ”
    Piérard-Franchimont C, E. Xhauflaire-Uhoda and, G. E. Pierard
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    TLDR Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.
    The 2006 document provides a review of dandruff, emphasizing its prevalence and the significant role of Malassezia spp. yeasts in its etiology. It explains that dandruff is a result of a reactive response of the scalp's epidermis to stimuli, with sebum being necessary but not solely responsible for the condition. The review also discusses the assessment of dandruff severity through clinical examination and squamometry, and its potential impact on hair loss, noting that dandruff can exacerbate hair shedding and may influence the progression of androgenic alopecia. Furthermore, it suggests that antifungal treatments, such as ketoconazole, could limit hair loss associated with dandruff and even stimulate hair growth, as observed in mice. The document underscores the importance of environmental factors and the microbial contribution to dandruff, as well as the implications for scalp health and hair cycle disturbances.
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       6 upvotes 5 years ago
      User is experiencing a very dry scalp with thick white flakes from using liquid minoxidil twice daily for a year. They use Nizoral every 10 days and are seeking advice for a healthier scalp, with a suggestion to use finasteride instead.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 1 year ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

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      in Research/Science  407 upvotes 3 weeks ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community Effect of nizoral shampoo on scalp

      in Ketoconazole  27 upvotes 1 month ago
      Nizoral shampoo effectively reduces scalp itchiness and dandruff, particularly for those using minoxidil, and may promote hair growth despite not being FDA-approved for this purpose. Users report significant improvements in scalp health and reduced itchiness with regular use.

      community Ru58841 completely got rid of my seb derm

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