Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness

November 2022 in “ eLife ”

Amanda Kowalczyk, Maria Chikina, Nathan L Clark

hairlessness hair growth keratin proteins FGF11 GLRA4 KRT2 KRT35 PKP1 PTPRM noncoding regions genetic changes regulatory sequences keratin

Studysummary This study found that specific genetic changes in both coding and noncoding regions may have independently driven the evolution of hairlessness in various mammalian species through accelerated evolution.

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