Search

for
Search:

GlossaryKeratin 2 (KRT2)

protein providing structural strength to skin, hair, and nails

Keratin 2 (KRT2) is a type of protein found in the outer layer of the skin, hair, and nails. It plays a crucial role in providing structural strength and resilience to these tissues, helping to protect them from damage and wear. Mutations in the KRT2 gene can lead to skin disorders such as ichthyosis bullosa of Siemens, which is characterized by blistering and scaling of the skin.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 258 results

research An Epistatic Effect of KRT25 on SP6 Is Involved in Curly Coat in Horses

13 citations , April 2018 in “Scientific Reports”

The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.

research Generation of the Krt24-CreERT2 Mouse Line Targeting Outer Bulge Hair Follicle Cells

March 2025 in “International Journal of Molecular Sciences”

The study created a mouse model to better understand hair follicle stem cells' role in hair growth and repair.

research A Small Deletion Hotspot in the Type II Keratin Gene mK6irs1/Krt2-6g on Mouse Chromosome 15, a Candidate for Causing the Wavy Hair of the Caracul (Ca) Mutation

53 citations , October 2003 in “Genetics”

The mK6irs1/Krt2-6g gene likely causes wavy hair in mice.

research Morphologic and Molecular Characterization of Two Novel Krt71 (Krt2-6g) Mutations: Krt71 Rco12 and Krt71 Rco13

51 citations , December 2006 in “Mammalian Genome”

research A Missense Mutation Within the Helix Termination Motif of KRT25 Causes Autosomal Dominant Woolly Hair/Hypotrichosis

33 citations , September 2017 in “Journal of Investigative Dermatology”

View more "krt2" in research →

Community Join

0 / 0 results

— no results