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    Glossary Keratin 1

    protein providing structural support in skin cells

    Keratin 1 (KRT1) is a type of protein found in the outer layer of the skin, playing a crucial role in providing structural integrity and resilience. It partners with Keratin 10 to form intermediate filaments, which help skin cells withstand mechanical stress and prevent damage. Mutations in the KRT1 gene can lead to skin disorders such as epidermolytic hyperkeratosis, characterized by blistering and thickened skin.

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    Research 10 of 1000+

    1. Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage Journal of Cell Science · 1996 · 441 citations
    2. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003 · 387 citations
    3. Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages during Skin Development The Journal of Cell Biology · 1998 · 318 citations
    4. Keratin 19: Predicted Amino Acid Sequence and Broad Tissue Distribution Suggest it Evolved from Keratinocyte Keratins. Journal of Investigative Dermatology · 1989 · 238 citations
    5. Keratin 15 Expression in Stratified Epithelia: Downregulation in Activated Keratinocytes Journal of Investigative Dermatology · 1999 · 198 citations
    6. Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2 British Journal of Dermatology · 1998 · 175 citations
    7. Keratin 17 modulates hair follicle cycling in a TN<i>Fα</i>-dependent fashion Genes & Development · 2006 · 169 citations
    8. Keratin 17 null mice exhibit age- and strain-dependent alopecia Genes & Development · 2002 · 122 citations
    9. The Tissue-dependent Keratin 19 Gene Transcription Is Regulated by GKLF/KLF4 and Sp1 Journal of Biological Chemistry · 2000 · 119 citations
    10. Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin. The Journal of Cell Biology · 1994 · 94 citations
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    Community 10 of 40

    1. Conflicting Hair Loss Treatment Advice at 18 with Medical Background Community · 25 Jul 2026
    2. Apparently, Keratin Microsphere products are already on the market. Gonna give it a college try, wish me luck! Reddit · 20 Sept 2024
    3. 22M loosing ground - 1MG fin + 2% Keto Shampoo Reddit · 15 Jul 2024
    4. Losing ground after 14 months of fin use and 11 months of min Reddit · 20 Jul 2022
    5. Balding absolutely ruined my life at 17. Reddit · 1 Aug 2024
    6. The truth about Dutasteride (w/ sources) Reddit · 24 Jan 2023
    7. Additional supplements / peptides to maximize finasteride benefit Reddit · 22 May 2026
    8. A Decade on Hairloss Battle Reddit · 28 Dec 2019
    9. Taurine supplements work for hair growth? Reddit · 23 Apr 2024
    10. Is it safe to get keratin treatment on transplanted hair? Reddit · 10 Aug 2024
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    Learn 5 of 6

    1. Azelaic Acid Acid used in acne and rosacea creams
    2. Biotin B vitamin, often sold as a hair supplement
    3. Keratin
    4. Hydrolyzed Keratin
    5. Alpha Keratin
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