Identification of Novel Glucocorticoid Receptor-Regulated Genes Involved in Epidermal Homeostasis and Hair Follicle Differentiation

    September 2007 in “ The Journal of Steroid Biochemistry and Molecular Biology ”
    Eva Donet, Pilar Bayo, Ézéquiel Calvo … Paloma Pérez
    Studysummary Glucocorticoid receptors help regulate genes important for skin health and hair growth.
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    Research cited in this study 12

    1. Peptidylarginine Deiminase Isoforms Are Differentially Expressed in Anagen Hair Follicles and Other Human Skin Appendages Journal of Investigative Dermatology · 2005
    2. Human Hair Follicles Display a Functional Equivalent of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Synthesize Cortisol The FASEB Journal · 2005
    3. Ectoderm-Targeted Overexpression of the Glucocorticoid Receptor Induces Hypohidrotic Ectodermal Dysplasia Endocrinology · 2005
    4. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    5. Krtap16: Characterization of a New Hair Keratin-Associated Protein Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13 Journal of Biological Chemistry · 2004
    6. The RAIG Family Member, GPRC5D, Is Associated With Hard-Keratinized Structures ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    7. Hox in Hair Growth and Development Die Naturwissenschaften · 2003
    8. Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-Associated Protein Genes on Chromosome 21q22.1 Journal of biological chemistry/˜The œJournal of biological chemistry · 2002
    9. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    10. Altered Skin Development and Impaired Proliferative and Inflammatory Responses in Transgenic Mice Overexpressing the Glucocorticoid Receptor The FASEB Journal · 2001
    11. Overexpression of Hoxc13 in Differentiating Keratinocytes Results in Downregulation of a Novel Hair Keratin Gene Cluster and Alopecia Development · 2001
    12. The Catalog of Human Hair Keratins Journal of biological chemistry/˜The œJournal of biological chemistry · 1999

    Related research 10

    1. Identification of Novel Glucocorticoid Receptor-Regulated Genes Involved in Epidermal Homeostasis and Hair Follicle Differentiation The Journal of Steroid Biochemistry and Molecular Biology · 2007
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    3. Expression of MK6a Dominant-Negative and C-Terminal Mutant Transgenes in Mice Has Distinct Phenotypic Consequences in the Epidermis and Hair Follicle Differentiation · 1999
    4. Modulation of Murine Hair Follicle Function by Alterations in Ornithine Decarboxylase Activity Journal of Investigative Dermatology · 1996
    5. Overexpression of Human Keratin 16 Produces a Distinct Skin Phenotype in Transgenic Mouse Skin Biochemistry and Cell Biology · 1995
    6. Skin-Specific Expression of a Truncated E1a Oncoprotein Binding to p105-Rb Leads to Abnormal Hair Follicle Maturation Without Increased Epidermal Proliferation The Journal of Cell Biology · 1993
    7. Keratin Phenotypes in Basal-Cell Carcinomas of the Skin International Journal of Oncology · 1993
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    9. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989
    10. Outer Root Sheath Keratinization in Anagen and Catagen of the Mammalian Hair Follicle: A Seventh Distinct Type of Keratinization in the Hair Follicle - Trichilemmal Keratinization PubMed · 1981