This review provides an overview of Hoxgenes, focusing on their evolutionary history, genomic organization, and roles in development, but reports no new study results.
This study found that estrogen, through estrogen receptors, can regulate the expression of the HOXC13 gene involved in hair follicle development, with MLL3 histone methylase playing a collaborative role.
65 citations
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July 2006 in “Journal of biological chemistry/The Journal of biological chemistry”
This study found that overexpression of Hoxc13 in GC13 mouse models affects hair follicle differentiation by interacting with medulla-specific genes, particularly Foxq1, suggesting a regulatory pathway for medulla differentiation.
This study shows that differences in Hoxc gene expression in hair follicle mesenchyme along the body axis contribute to regional variations in mammalian hair growth.