Krtap16: Characterization of a New Hair Keratin-Associated Protein Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13

    September 2004 in “ Journal of Biological Chemistry
    Nathanael Pruett, Tatiana V. Tkatchenko, Luis Felipe Jave‐Suárez … Alexander Awgulewitsch
    Studysummary This study provides evidence supporting a regulatory relationship between the transcriptional regulator Hoxc13 and Krtap16 genes, which are crucial for proper hair growth in mice.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jbc.org →
    Discuss this study in the Community →

    Research cited in this study 23

    1. Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 21 in Fond Memory of Dr. Peter Steinert ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    2. Hox in Hair Growth and Development Die Naturwissenschaften · 2003
    3. Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-Associated Protein Genes on Chromosome 21q22.1 Journal of biological chemistry/˜The œJournal of biological chemistry · 2002
    4. Keratin 17 Null Mice Exhibit Age- And Strain-Dependent Alopecia Genes & Development · 2002
    5. HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression Journal of Biological Chemistry · 2002
    6. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    7. Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21 Journal of biological chemistry/˜The œJournal of biological chemistry · 2001
    8. Overexpression of Hoxc13 in Differentiating Keratinocytes Results in Downregulation of a Novel Hair Keratin Gene Cluster and Alopecia Development · 2001
    9. Characterization of a 300 Kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain Journal of Investigative Dermatology · 2000
    10. Expression of MK6a Dominant-Negative and C-Terminal Mutant Transgenes in Mice Has Distinct Phenotypic Consequences in the Epidermis and Hair Follicle Differentiation · 1999
    11. Pmg-1 and Pmg-2 Constitute a Novel Family of KAP Genes Differentially Expressed During Skin and Mammary Gland Development Mechanisms of Development · 1999
    12. The Catalog of Human Hair Keratins Journal of biological chemistry/˜The œJournal of biological chemistry · 1999
    13. Isolation and Characterization of Mouse High-Glycine/Tyrosine Proteins Journal of Biological Chemistry · 1997
    14. Mutations in the Hair Cortex Keratin HHB6 Cause the Inherited Hair Disease Monilethrix Nature Genetics · 1997
    15. Targeted Expression of SV40 T Antigen in the Hair Follicle of Transgenic Mice Produces an Aberrant Hair Phenotype Journal of cell science · 1995
    16. Formation and Structure of Human Hair Birkhäuser Basel eBooks · 1995
    17. Isolation and Characterization of a Novel Hair Follicle-Specific Gene, Hacl-1 Journal of Investigative Dermatology · 1994
    18. Organization and Expression of Hair Follicle Genes ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    19. Organization and Expression of Hair Follicle Genes ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    20. Sequence, Expression, and Evolutionary Conservation of a Gene Encoding a Glycine/Tyrosine-Rich Keratin-Associated Protein of Hair Journal of Biological Chemistry · 1993
    21. The Secret Life of the Hair Follicle Trends in genetics · 1992
    22. Regulation of Keratin Gene Expression in Hair Follicle Differentiation Annals of the New York Academy of Sciences · 1991
    23. Cyclic Hair Loss and Regrowth in Transgenic Mice Overexpressing an Intermediate Filament Gene The EMBO Journal · 1990

    Related research 6

    1. Keratin Microspheres As Promising Tool For Targeting Follicular Growth ACS applied bio materials · 2024
    2. Characterization and Expression Analysis of the Hair Keratin Associated Protein KAP26.1 British Journal of Dermatology · 2008
    3. Hair Follicle-Specific Keratins And Their Diseases Experimental cell research · 2007
    4. Keratins of the Human Hair Follicle International review of cytology · 2005
    5. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    6. Hair Keratin Pattern in Human Hair Follicles Grown In Vitro Experimental dermatology · 2003