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Did you mean immunohistochemical analysis?

GlossaryImmunostaining (immunohistochemical analysis)

technique using antibodies to detect specific proteins in tissues

Immunofluorescence (IF) is a laboratory technique used to visualize the presence and location of specific proteins or antigens in cells or tissue sections by using antibodies that are chemically linked to a fluorescent dye. When these antibodies bind to their target, the fluorescent dye can be seen under a microscope with the appropriate light, allowing researchers to study the distribution and abundance of the proteins of interest.

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research Krtap16: Characterization of a New Hair Keratin-Associated Protein Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13

47 citations , September 2004 in “Journal of Biological Chemistry”

Hoxc13 regulates specific hair protein genes on mouse chromosome 16.

research Cytokeratin 15 Expression in Trichoepitheliomas and a Subset of Basal Cell Carcinomas Suggests They Originate from Hair Follicle Stem Cells

133 citations , March 1999 in “Journal of Cutaneous Pathology”

Trichoepitheliomas and some basal cell carcinomas likely come from hair follicle stem cells.

Autosomal Recessive Transmission of a Rare KRT74 Variant Causes Hair and Nail Ectodermal Dysplasia: Allelism with Dominant Woolly Hair/Hypotrichosis

research Autosomal Recessive Transmission of a Rare KRT74 Variant Causes Hair and Nail Ectodermal Dysplasia: Allelism with Dominant Woolly Hair/Hypotrichosis

21 citations , April 2014 in “PLoS ONE”

A rare gene variant causes hair and nail issues in a family.

Targeted Expression of Human Vitamin D Receptor in the Skin Promotes the Initiation of the Postnatal Hair Follicle Cycle and Rescues Alopecia in Vitamin D Receptor Null Mice

research Targeted Expression of Human Vitamin D Receptor in the Skin Promotes the Initiation of the Postnatal Hair Follicle Cycle and Rescues Alopecia in Vitamin D Receptor Null Mice

57 citations , April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Vitamin D receptor is crucial for starting hair growth after birth.

research Biochemical and Immunohistochemical Analyses of Keratin Expression in Basal Cell Carcinoma

37 citations , May 1998 in “Journal of Dermatological Science”

Basal cell carcinoma shows keratin patterns similar to undifferentiated hair follicle cells.

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community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 415 upvotes 11 months ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Another clueless guy fearmongering and spreading misinformation

in Chat 251 upvotes 2 years ago

The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 676 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.