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GlossaryCorticosteroids (Glucocorticoid)

hormones reducing inflammation and immune response, often prescribed for autoimmune diseases

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex and are used in medicine to reduce inflammation and suppress the immune system. They are commonly prescribed for conditions like asthma, arthritis, and autoimmune diseases, and can be administered in various forms, including oral pills, topical creams, and injections.

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Recent Advances in the Molecular Mechanisms Determining Tissue Sensitivity to Glucocorticoids: Novel Mutations, Circadian Rhythm, and Ligand-Induced Repression of the Human Glucocorticoid Receptor

research Recent Advances in the Molecular Mechanisms Determining Tissue Sensitivity to Glucocorticoids: Novel Mutations, Circadian Rhythm, and Ligand-Induced Repression of the Human Glucocorticoid Receptor

62 citations , August 2014 in “BMC Endocrine Disorders”

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

research 5α-Reduced Glucocorticoids: A Story of Natural Selection

46 citations , September 2011 in “Journal of Endocrinology”

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

research Regulation of Human Dermal Papilla Cell Production of Insulin-Like Growth Factor Binding Protein-3 by Retinoic Acid, Glucocorticoids, and Insulin-Like Growth Factor-1

37 citations , June 1996 in “Journal of cellular physiology”

Retinoic acid, glucocorticoids, and IGF1 increase IGFBP-3 production in human dermal papilla cells, affecting hair growth.

research Skin and Glucocorticoids: Effects of Local Skin Glucocorticoid Impairment on Skin Homeostasis

18 citations , October 2014 in “Experimental Dermatology”

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

research Glucocorticoids and Risk of Venous Thromboembolism in Asthma Patients Aged 20–59 Years in the United Kingdom's CPRD 1995–2015

18 citations , January 2022 in “Clinical Epidemiology”

Higher doses of glucocorticoids increase the risk of blood clots in asthma patients.

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community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 1 year ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community Thoughts about ORAL ketoconazole? (pills)

in Ketoconazole 1 week ago

Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

community AA and Hirsutism but T levels are normal

in Female 6 upvotes 4 years ago

27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

community No luck with meds, Check your Cortisol.

in Treatment 37 upvotes 1 year ago

Cortisol from stress can cause hair loss. Controlling cortisol levels improved the effectiveness of finasteride for hair regrowth.

community NootBro Recommendations… How Do We Feel

in Research/Science 9 upvotes 1 year ago

The conversation is about hair loss treatments, specifically a stack including topical Ashwagandha, Copper Peptide, Gotu Kola, Ketoconazole, and PDA. One user found Topical and Sub-Q GHK-CU effective.

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