Age-Related Changes in Endogenous Glucocorticoids, Gonadal Steroids, Endocannabinoids, and Their Ratios in Plasma and Hair from Male C57BL/6 Mice

    October 2020 in “ General and comparative endocrinology ”
    Liuxi Chu, Wenhua Liu, Jia Deng, Yan Wu, H. Yang, Wei Wang, Ahad Hussain, Na Li, Dongrui Zhou, Huihua Deng
    TLDR Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.
    The study examined age-related changes in glucocorticoids, gonadal steroids, endocannabinoids, and their ratios in plasma and hair of male C57BL/6 mice from 21 days to 10 months old. It found that concentrations of these compounds varied with age, with hair samples showing less variability than plasma, suggesting hair as a more stable biomarker. The ratios between these compounds could serve as reliable indicators of interactions within and between the HPA, HPG axes, and ECS, providing insights into the endocrine system's age-dependent activities and interactions.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    5 / 5 results

      community We Need A Solution For The Inflammatory Response related To AGA

      in Research/Science  16 upvotes 7 months ago
      The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

      community AA and Hirsutism but T levels are normal

      in Female  6 upvotes 4 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community NootBro Recommendations… How Do We Feel

      in Research/Science  10 upvotes 10 months ago
      The conversation is about hair loss treatments, specifically a stack including topical Ashwagandha, Copper Peptide, Gotu Kola, Ketoconazole, and PDA. One user found Topical and Sub-Q GHK-CU effective.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 5 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

    Similar Research

    5 / 1000+ results